Exercise promotes osteogenic differentiation by activating the long non-coding RNA H19/microRNA-149 axis.

Background: Regular physical activity during childhood and adolescence is beneficial to bone development, as evidenced by the ability to increase bone density and peak bone mass by promoting bone formation.

Aim: To investigate the effects of exercise on bone formation in growing mice and to investigate the underlying mechanisms.

Methods: 20 growing mice were randomly divided into two groups: Con group (control group, = 10) and Ex group (treadmill exercise group, = 10).

BSR and Full-Length Transcriptome Approaches Identified Candidate Genes for High Seed Ratio in .

(1) Background: C. vietnamensis is very suitable for growth in the low hilly areas of southern subtropical regions. Under appropriate conditions, the oil yield of C.

Transcriptome analysis of the testes of male chickens with high and low sperm motility.

The reproductive performance of chicken breeders has significant economic importance in the poultry industry, and sperm motility is an indicator of reproductive performance. This study performed RNA-seq of the testes of Gushi chicken roosters with high and low sperm motility and identified differentially expressed RNAs involved in sperm motility. RNA-seq analysis showed that 73 and 67 differentially expressed mRNAs were up- and downregulated, and 47 and 56 differentially expressed long non-coding RNAs were up- and downregulated, respectively.

Relationship between Methylation of FHIT and CDH13 Gene Promoter Region and Liver Cancer.

In order to demonstrate the relationship between methylation of fragile histidine triad (FHIT) and T-cadherin/H-cadherin (CDH13) genes and liver cancer, the methylation status of FHIT and CDH13 was detected in healthy individuals and in Mongolian and Han patients with liver cancer. The phenol-chloroform method was used to extract genomic DNA. The methylation specific polymerase chain reaction method was applied to detect the methylation status of FHIT and CDH13.

Analysis of the spatial distribution of collectors in dust scrubber based on image processing.

The spatial distribution of the collectors in dust scrubber is key in determining the effectiveness of the dust removal process. In the present study, a high-speed camera was used to capture images of the distribution of the collectors. Some of the image information was extracted by image processing, such as the gray mean (GM), the angular second moment (ASM), and the entropy (ENT) from the gray-level co-occurrence matrix of the image.

Structural analysis and antioxidant activities of neutral polysaccharide isolated from Epimedium koreanum Nakai.

The structure and antioxidant activity of a neutral polysaccharide (named as EFPN-1) from Epimedium koreanum Nakai were studied. Based on the results from high performance gel permeation chromatography, methylation GC-MS and 1D/2D nuclear magnetic resonance spectroscopy, EFPN-1 was a branched polysaccharide with a molecular weight of 21.9 kD and containing over 60% of glucose.

Systematic fractionation and immunoenhancement of water-soluble polysaccharides isolated from fruit of Morus alba L.

In this study, we obtained and fractionated systematically the polysaccharides of Fructus mori fruit by the sequential use of water extraction, ethanol precipitation and ion-exchange chromatography. The sugar contents of FPA-1, FPA-2, FPA-4 and FPA-5 were estimated to be 75.70%, 67.

A pro-atherogenic HDL profile in coronary heart disease patients: an iTRAQ labelling-based proteomic approach.

Objectives: This study aims to compare the protein composition of high-density lipoprotein (HDL) particles in coronary heart disease (CHD) patients and controls by proteomic methods.

Background: HDL has been reported to exert pro-atherogenic properties in CHD patients. Accumulating evidence indicates that HDL composition, rather than the HDL-C level, determines its functions.

The relationship between serum amyloid A and apolipoprotein A-I in high-density lipoprotein isolated from patients with coronary heart disease.

Background: Alteration in the protein composition of high-density lipoprotein (HDL) has been proposed as a mechanism for the development of coronary heart disease (CHD). In HDL, an increase in serum amyloid A protein (SAA) accompanying the decrease in apolipoprotein A-I (apoA-I) has been found during the acute inflammation period. However, whether this phenomenon persists in CHD patients, a disease related to inflammation, is unknown.

Sophorolipid production from delignined corncob residue by Wickerhamiella domercqiae var. sophorolipid CGMCC 1576 and Cryptococcus curvatus ATCC 96219.

Delignined corncob residue hydrolysate (DCCRH) and detoxified DCCRH were used for single cell oil (SCO) and single cell protein (SCP) production of Cryptococcus curvatus ATCC 96219 and for sophorolipid (SL) production of Wickerhamiella domercqiae var. sophorolipid CGMCC 1576. Both C.

[Surfactant proteins-A and D as important serum markers for interstitial lung disease in patients with polymyositis or dermatomyositis].

Objective: To explore the possible diagnostic values of serum surfactant protein-A (SP-A) and surfactant protein-D (SP-D) for interstitial lung diseases (ILD) in patients with polymyositis or dermatomyositis (PM/DM).

Methods: Serum MCP-1 concentrations were measured by enzyme-linked immunosorbent assay (ELISA) in 100 adult PM/DM patients, 20 patients with pulmonary infection and 42 healthy controls. And the association with their clinical features and serum levels of SP-A and SP-D was analyzed.

Clinical significance of peripheral blood lymphocyte subsets in patients with polymyositis and dermatomyositis.

Peripheral blood lymphocyte subsets were determined by flow cytometry in 89 Chinese patients with polymyositis (PM) and dermatomyositis (DM). We aimed to investigate the clinical significance of peripheral blood lymphocyte subsets in PM/DM. Patients with active DM showed significant decreases in numbers of CD3(+) cells, CD3(+)CD4(+) cells, and CD3(+)CD8(+) cells, as compared to patients with inactive DM and healthy controls (P < 0.

[Measurement and clinical significance of serum monocyte chemoattractant protein-1 in patients with polymyosits/dermatomyosits].

Objective: To analyze the correlated clinical significance by testing the serum monocyte chemoattractant protein-1 (MCP-1) levels of patients with polymyositis/dermatomyositis (PM/DM).

Methods: The sera from 100 adult PM/DM patients, 20 patients with pulmonary infection and 42 healthy controls were selected. The serum MCP-1 concentrations were detected by enzyme-linked immunosorbent assay (ELISA).

Intravenous immunoglobulin therapy in adult patients with polymyositis/dermatomyositis: a systematic literature review.

The objectives of this study are to review and summarize published information on the use, effectiveness, and adverse effects of intravenous immunoglobulin (IVIG) in patients with polymyositis (PM) or dermatomyositis (DM) and to search MEDLINE and CNKI (Chinese) databases from 1985 to 2011 to retrieve clinical research articles concerning IVIG in adult patients with PM/DM. Of the 14 articles selected, two were randomized controlled trials, nine prospective open studies, and three retrospective studies with a total of 308 adult patients. IVIG has been used successfully in the treatment of PM/DM.

[Glucagon like peptide-1 inhibits high glucose-induced injury of oxidative stress in cardiomyocytes of neonatal rats].

The present study was to investigate the effect of glucagon like peptide-1 (GLP-1) on high glucose-induced oxidative stress of cardiomyocytes and the possible role of the PI3K-Akt signal path in this process in the neonatal SD rats. With enzymatic digestion and immunofluorescence identification, cardiomyocytes after 72-96 h of primary culture were used in experiment. The cells were divided into 5 groups: normal control group, high glucose group, high glucose + GLP-1 group, high glucose + GLP-1 + LY294002 group and high osmolarity control group.

[A clinical study of femoral head osteonecrosis in patients with systemic lupus erythematosus.].

Objective: To investigate the clinical features of osteonecrosis of the femoral head (ONFH) in patients with systemic lupus erythematosus (SLE).

Methods: The consecutive 461 SLE patients who underwent inpatient care in China-Japan Friendship Hospital were reviewed, the clinical data of 32 cases complicated with ONFH and 64 without ONFH as control was studied.

Results: The incidence of ONFH in 461 SLE patients was 6.

Device design and simulation for GaN based dual wavelength LEDs.

A comprehensive optical model for dual wavelength LEDs is developed using optical ray tracing programs. Optical dispersion of GaN, InGaN, and AlGaN is also included in this numerical model. The light extraction efficiency of LEDs can be calculated based on LED structure and material properties.

[A clinical study of tuberculosis infection in systemic lupus erythematosus].

Objective: To investigate the characteristics and related risk factors associated with Tuberculosis(TB) in patients with systemic lupus erythematosus (SLE) who received glucocorticoid and immunosuppressive therapy.

Methods: Among the 452 SLE patients underwent the treatment of glucocorticoid and immunosuppressive agent, the clinical data was reviewed and summarized retrospectively.

Results: 42 of 452 (9.

GaN-based distributed Bragg reflector for high-brightness LED and solid-state lighting.

A comprehensive numerical model for distributed Bragg reflectors (DBRs) based on thin-film optics is developed. Detailed refractive-index calculations for GaN, AlN, AlGaN, and InGaN can also be included in this numerical model. This model can predict DBR performances for refractive-index variations, layer-thickness fluctuations, and the number of quarter-wave stack pairs in DBR as well different light polarizations.

Numerical model of wavelength conversion through cross-gain modulation in semiconductor optical amplifiers.

A steady-state numerical model of wavelength conversion through cross-gain modulation in semiconductor optical amplifiers is described, which includes the spatial variations of the carrier density, gain coefficient, differential gain, and internal loss. Of particular interest is the analytic gain coefficient model, which is applied to the semiconductor optical amplifier converter problem for the first time to our knowledge. The model is used to compare performances of upconverters and downconverters for cases of long and short device lengths, and in large and small signal regimes.