Publications by authors named "Dong-Won Son"
HemoHIM is a functional food ingredient comprising a triple herbal combination of extracts from Nakai, Makino, and Pallas. It was developed to aid the recovery of impaired immune function. Although it is widely used to treat various immune disorders in Korea, its potential toxicity has not been extensively investigated.
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- * In experiments with rats, HemoHIM G showed no signs of acute toxicity even at high doses (up to 5000 mg/kg/day) and did not lead to any adverse effects after 13 weeks of repeated dosing.
- * Tests conducted for potential genotoxicity confirmed that HemoHIM G is non-mutagenic and non-clastogenic, indicating it is safe for use as a food ingredient.
Factors associated with parental knowledge and attitudes toward pediatric concussions in Korea.
Clin Exp Emerg Med
December 2024
Objective: This study investigated the status and evaluated factors associated with knowledge and attitudes regarding pediatric concussions among Korean parents of children aged 6 to 18 years.
Methods: A cross-sectional online survey was employed to collect data from a panel of parents in Korea in 2023. To assess knowledge and attitudes regarding concussions, participants completed a validated questionnaire.
Article Synopsis
- A rotating shaft and its bearings can generate voltage and current, leading to electrical corrosion that shortens motor life and causes safety issues.
- To combat this, the study developed a new electrical corrosion protection device that detects current and potential differences, creating a feedback system to minimize these issues.
- Testing on a rotating shaft confirmed the device could keep the potential difference below 2 mV, significantly improving motor stability and efficiency, with successful application on a merchant ship for 30 days.
Article Synopsis
- In vivo inhalation toxicity tests are limited due to economic and ethical constraints, prompting the development of an in vitro acute inhalation toxicity test method.
- The pre-validation study confirmed the transferability and reproducibility of the Calu-3 cytotoxicity assay across three independent institutions, showing excellent agreement in results for 20 test substances.
- The predictive capacity was evaluated with 77 test substances, achieving an accuracy of 72.73% and a ROC curve area of 0.77, indicating that the in vitro method is a reliable alternative for screening acute inhalation toxicity.
Two endoglucanases with processive cellulase activities, produced from Fomitopsis palustris grown on 2% microcrystalline cellulose (Avicel), were purified to homogeneity by anion-exchange and gel filtration column chromatography systems. SDS-PAGE analysis indicated that the molecular masses of the purified enzymes were 47 kDa and 35 kDa, respectively. The amino acid sequence analysis of the 47-kDa protein (EG47) showed a sequence similarity with fungal glycoside hydrolase family 5 endoglucanase from the white-rot fungus Phanerochaete chrysosporium.
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