Protective role of licochalcone B against ethanol-induced hepatotoxicity through regulation of Erk signaling.

Objectives: Oxidative stress has been established as a key cause of alcohol-induced hepatotoxicity. Licochalcone B, an extract of licorice root, has shown antioxidative properties. This study was to investigate the effects and mechanisms of licochalcone B in ethanol-induced hepatic injury in an study.