Acute Effects of Individual Exposure to Fine Particulate Matter on Pulmonary Function in Schoolchildren.

Objective: This panel study aimed to determine the acute effects of exposure to fine particulate matter (PM ) on schoolchildren's pulmonary function.

Methods: We selected 51 schoolchildren aged 9-12 years attending a full-time boarding school in Beijing, China, measured the indoor and outdoor PM concentrations for five consecutive days, calculated the PM time-weighted individual exposure levels based on the school micro-environmental concentrations and the time activity pattern recorded by schoolchildren, measured schoolchildren's pulmonary function on the fifth day. The survey was performed three times from December 2018 to April 2019.

PM2.5 exposure induces vascular dysfunction via NO generated by iNOS in lung of ApoE-/- mouse.

PM2.5 exposure exacerbates cardiovascular diseases via oxidative stress and inflammation, the detailed mechanism of which is unclear. In this study, the effects of oxidative stress and inflammation, as well as vascular structure and function were studied by multiple PM2.

PM aggravates diabetes via the systemically activated IL-6-mediated STAT3/SOCS3 pathway in rats' liver.

PM exposure aggravates type 2 diabetes, in which inflammatory factors play an important role. In this study, we aimed to explore the mechanisms responsible for aggravating diabetes after PM exposure, and study the roles of inflammatory factors in insulin-resistant type 2 diabetes. Our study indicated that short-time PM exposure enhances insulin resistance in type 2 diabetic rats and significantly raises inflammatory factors, including IL-6, TNF-α, and MCP-1, in lungs.

Measurement Uncertainty Assessment for Determination of Allura Red in Puffed Food by HPLC.

This study aimed to assess the measurement uncertainty of a new method for determination of allura redin food by high performance liquid chromatography (HPLC). The uncertainty of mathematical model of allura red is based on Europe for Analytical Chemistry(EURACHEM) guidelines. The sources and components of uncertainty were calculated, including recovery, working solution, sample mass, final volume, response of standard solution, response of sample solution.

PM2.5 induces autophagy-mediated cell death via NOS2 signaling in human bronchial epithelium cells.

The biggest victim of ambient air pollution is the respiratory system. Mainly because of the harmful components, especially the particulate matters with an aerodynamic diameter of ≤ 2.5µm (PM2.

Autophagy Induced FHL2 Upregulation Promotes IL-6 Production by Activating the NF-κB Pathway in Mouse Aortic Endothelial Cells after Exposure to PM2.5.

Epidemiological and clinical studies have increasingly shown that fine particulate matter (PM2.5) is associated with cardiovascular morbidity and mortality, which share the common feature of PM2.5-induced vascular inflammation; however, the underlying mechanisms of how PM2.

[Application of ICP-MS and ICP-AES for Studying on Source Apportionment of PM2.5 during Haze Weather in Urban Beijing].

To investigate the characteristics of chemical constitute and pollution sources of aerosol fine particulate matter during haze-fog day in Beijing in winter 2013. The samples of PM2.5 were collected in Beijing from January to February, 2013.

Prevalence and Treatment of Children's Asthma in Rural Areas Compared with Urban Areas in Beijing.

Background: The prevalence of childhood asthma has been increasing in China. This study aimed to compare the prevalence, diagnosis, and treatment of asthmatic children from urban and rural areas in Beijing, China.

Methods: Schools, communities, and kindergartens were randomly selected by cluster random sampling from urban and rural areas in Beijing.

[Assessment of haze-related human health risks for four Chinese cities during extreme haze in January 2013].

Objective: To evaluate the human health risks (premature death risk as an indicator) in Beijing, Shanghai, Guangzhou and Xi'an during extreme haze in January 2013.

Methods: The daily average particulate matter ≤ 2.5 µm in aerodynamic diameter (PM2.

[Epidemiological survey of children asthma prevalence in Beijing urban area].

Objective: To explore the prevalence, diagnosis and management of childhood asthma in Beijing urban area.

Methods: Multi-stage, stratified and random cluster sampling was used to recruit children born during November 1, 1995 to October 31, 2010 from Beijing or other provinces but residing in Beijing for over half a year. The same screening questionnaires for the third national epidemiological survey of children's asthma were distributed to parents of children at schools, kindergartens and communities during October 2010 to March 2011.

Transient receptor potential vanilloid 2 (TRPV2), a potential novel biomarker in childhood asthma.

Background: The presence of transient receptor potential vanilloid 2 (TRPV2) in human peripheral blood cells may suggest a role under pathological conditions. The aim of this study was to explore the relationship between the expression profile of TRPV2 gene and childhood asthma in the north of China. The effects of allergens exposure on the expression of TRPV2 gene were also investigated.

Association of polymorphisms of STAT6 and SO(2) with Chinese childhood asthma: a case-control study.

Objective: To investigate the association of polymorphisms of STAT6 gene and air pollutants of PM(10), NO(2), and SO(2), with asthma in Chinese children.

Methods: 418 subjects aged 14 years and under were recruited in a case-control study. The association between STAT6 polymorphisms and childhood asthma were tested by allele frequency, genotype analysis, and MDR analysis.

[Determination of trace elements Be, Cd, as and Pb in air of residential areas by inductively coupled plasma-mass spectrometry coupled with ultrasonic leaching].

In the present paper, the method for determining the trace elements Be, Cd, As and Pb in air of residential areas by inductively coupled plasma-mass spectrometry was established. Ultrasonic leaching procedures were applied to extract the trace elements from the filter membrane of the atmospheric particulates. The operating condition of the instrument was optimized.

Immunological effect of PM2.5 on cytokine production in female Wistar rats.

Objective: To investigate the immunological effect of PM2.5 on cytokine production in female Wistar rats.

Methods: Female Wistar rats were given 0.

[Histopathology of lung of rats exposed to suspension of PM(2.5) with silver staining].

Objective: To observe the histopathological changes of the lung of rats which exposed to the suspension of PM(2.5) and detect the effect of silver staining showing dust particles deposited in the lungs.

Methods: The dissociative PM(2.

Characteristics and seasonal variations of PM2.5, PM10, and TSP aerosol in Beijing.

Objective: To investigate the seasonal characteristics and the sources of elements and ions with different sizes in the aerosols in Beijing.

Methods: Samples of particulate matters (PM2.5), PM10, and total suspended particle (TSP) aerosols were collected simultaneously in Beijing from July 2001 to April 2003.

[Effects of formaldehyde on the activity of superoxide dismutases and glutathione peroxidase and the concentration of malondialdehyde].

This review focus on the effects of formaldehyde on the activity of superoxide dismutases (SOD), glutathione peroxidase (GSH-Px) and the concentration of malondialdehyde (MDA) in recent years. It is showed formaldehyde having effect on lipid peroxidation by many studies of animal experiment and occupational group, it can decrease the activity of SOD and GSH-Px, increase the concentration of MDA, there are dose-response relationship between those lipid peroxidation index and the concentration of formaldehyde too. In future study, the animal experiment and the people's late effect of low dose formaldehyde exposure should be pay more attention.

Monitoring of pollution of air fine particles (PM2.5) and study on their genetic toxicity.

Objective: To compare PM2.5 pollation level between the city of coal-fuel pollution (Taiyuan) and the city of pollution mixed with coal fuels and vehicle exhausts (Beijing), to analyze the concentration of B[a]p and Pb in the pollutants, and to study the DNA damage by PM2.5.

[Preliminary study on the relationship between chronic sinusitis histomorphology and aerosol].

Objective: To observe the relationship between histomorphological changes in mucosa of chronic sinusitis (CS) and aerosol particles.

Methods: The ethmoidal sinus mucus specimens of 60 patients with CS type I, II and III, and 16 cases of normal controls were collected. Meanwhile the pulmonary specimens in autopsy of 5 adult and 5 fetus cases were also collected.