Inhibition of heme oxygenase-1 enhances the chemosensitivity of laryngeal squamous cell cancer Hep-2 cells to cisplatin.

It has been previously reported that cisplatin is a well-known anticancer drug being used against a wide range of malignancies including head and neck, ovarian and non-small cell lung carcinoma, and demonstrated its anticancer activity by reacting with DNA or changing cell structure, immune response, reactive oxygen species level (ROS). In this research we proved that cisplatin induced cell injuries and heme oxygenase-1 (HO-1) expression in laryngeal squamous cell cancer Hep-2 cells through ROS generation. The induction of HO-1 clearly protected Hep-2 cells from cisplatin-induced cell death and ROS reaction, and the inhibitor of HO-1 enhanced the cell death and ROS generation induced by cisplatin.

[Epidemiological survey of childhood asthma in 2010 in urban Baotou, China].

Objective: To investigate the prevalence rate of childhood asthma in 2010 in urban Baotou, China, as well as the characteristics of attacks and the status of diagnosis and treatment of childhood asthma.

Methods: More than 10 000 children (0-14 years) were selected from 3 secondary schools, 3 primary schools, 6 kindergartens, and 4 community vaccination sites in urban Baotou by cluster random sampling between September 2009 and August 2010. A standardized preliminary questionnaire was used for screening out suspected cases, which were then confirmed or excluded by a clinician; the confirmed cases underwent further questionnaire survey.

First principles study of periodic size dependent band gap variation of Cu doped ZnO single-wall nanotube.

In this contribution, the size dependent band gap variation of (Zn(4/6)Cu(2/6)O)(L)/(Zn(5/6)Cu(1/6)O)(L) (L is the periodic size) superlattices are investigated with the change of L. The results show that the variation tendency of band gap appears a minimum in S(4) (L = 4) which is nearly a conductor. The band gap of S(3) (L = 3) and S(5) (L = 5) also decrease obviously compared to the other three configurations.

[Effect of the degree of muscle relaxation on motor-evoked potential elicited by transcranial electrical stimulation in spine surgery].

Objective: To study the effect of the degree of muscle relaxation on motor-evoked potential elicited by transcranial electrical stimulation in patients undergoing spine surgery.

Methods: Sixty ASA I or II patients undergoing spine surgery were randomly divided into 5 groups (n=12). After an initial intubation, continuous cisatracurium infusion was administered with continuous monitoring of T1.

[Effect of gensenoside Rg3 on apoptosis of Hep-2 and expression of HIF-1alha in human laryngeal cancer cell line under anoxic conditions].

Objective: To study the mechanism and effect of gensenoside Rg3 on Hep-2 Cell Line during the normoxia and hypoxia.

Methods: Hep-2 Human Laryngeal Cancer Cell Line was cultured under anoxic conditions, and set the normal control group and positive control group (DDP). MTT was used to observe the growth inhibition rates of Hep-2 Human Laryngeal Cancer Cell by Rg3; The cell cycle and cell apoptosis analysis were detected by FCM.

Power relation and condom use in commercial sex behaviors.

Objective: To explore whether condom use is influenced by power relation in commercial sex behaviors.

Methods: Variables were designed to measure the power relation in commercial sex behaviors based on the theory of gender and power relation and data were collected from male sexually transmitted diseases (STD) patients and female commercial sex workers (FSWs) working at recreation centers or being detained in a women education center to identify the relationship between condom use and power relation in male and female respondents using bivariate and multiple regression analysis.

Results: A significant relationship was identified between power relation and female condom use, the higher the score of power relations, the higher frequency the condom use, but no similar result was found in males.

[Expression of CD44 and nm23-H1 protein in the primary and metastatic lymph node lesions in supraglottic and hypopharyngeal cancer].

Objective: To study the metastasis feature of the primary and metastatic lymph node lesions in supraglottic or hypopharyngeal cancer.

Methods: The expression of CD44 and nm23-H1 in specimens from the primary and metastatic lymph node lesions of the 41 cases with supraglottic or hypopharyngeal cancer were studied with immunohistochemistry method and flow cytometry.

Results: No correlation was found between the expression of CD44, nm23-H1 and the tumor differentiation of the supraglottic or hypopharyngeal cancer, but their expression related with the clinical staging.

Dynamics of typical agricultural landscape and its relationship with water resource in inland Shiyang River watershed, Gansu province, northwest China.

Shiyang River basin is located in Hexi Corridor, central-west Gansu province, northwest China. It is an area of typical arid to semiarid features. Based on the TM image of Liangzhou oasis and Minqin oasis in 1986 and 2000, this paper calculated and analyzed the changes of percentage and area of land use/cover types, and also have got the transformation matrix of the landscape mosaics.