1,2-Diphenyl--carborane and Its Chromium Derivatives: Synthesis, Characterization, X-ray Structural Studies, and Biological Evaluations.

The objective of this study is to design and synthesize substituted η-chromium(0) tricarbonyl metal complexes carrying -carborane units as potential boron neutron capture therapy (BNCT) agents. In this study, 1,2-diphenyl--carborane () units were used as starting materials to generate biologically active species. We investigated how the structural changes of substituted with chromium(0) tricarbonyl affect the biological properties, and 1-(Phenyl-η-chromium(0) tricarbonyl)-2-phenyl--carborane () and 1,2-bis(phenyl-η-chromium(0) tricarbonyl)--carborane () species were produced in moderate yields.