Publications by authors named "Dong-Dong Qiao"
The nearly complete mitochondrial genome of the door snail (Stylommatophora: Clausiliidae) and phylogenetic analysis.
Mitochondrial DNA B Resour
November 2024
The family Clausiliidae was proposed as a model for studying the diversity of breeding biology in land snails. This study assembled a nearly complete mitogenome (15,417 bp) for the clausiliid snail . The mitogenome includes 13 protein-coding genes (PCGs), two ribosomal RNAs, and 22 transfer RNAs, with a gene order consistent with other clausiliids.
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- - The study investigates how specific genetic polymorphisms in the NEDD4 gene and experiences of childhood trauma influence symptoms of schizophrenia, involving 289 patients and 487 control participants.
- - They found that patients with certain genotypes (like rs2303579 CC and rs3088077 TT) exhibited significantly higher symptom scores, and those with a family history of psychosis reported worse symptoms overall.
- - Additionally, various types of childhood trauma (such as physical and sexual abuse) were linked to poorer cognitive scores, and the interactions between these genetic factors and trauma were particularly impactful for individuals with a family background of psychosis.
Background: Psychotic major depression (PMD) is a subtype of depression with a poor prognosis. Previous studies have failed to find many differences between patients with PMD and those with non-psychotic major depression (NMD) or schizophrenia (SZ). We compared sociodemographic factors (including season of conception) and clinical characteristics between patients with PMD, NMD, and schizophrenia.
View Article and Find Full Text PDFBackground: The nonhomologous end-joining (NHEJ) pathway is the main mechanism repairing DNA double-strand breaks (DSBs) in human cells. This research was designed to study the association between selected variants in NHEJ members and esophageal squamous cell carcinoma (ESCC).
Methods: Two single nucleotide polymorphisms (SNPs), PRKDC (rs7003908) and X-ray repair cross complementing group 4 (XRCC4; rs1805377), were genotyped in a total of 189 patients with ESCC and 189 unrelated control individuals in a high-risk area for ESCC in North China, and the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was applied.
Infant colic, excessive crying of unknown cause, is a major burden to families and effects about 10-30 % of infants. Despite decades of research, the exact cause and treatment of infant colic has remained elusive. The use of Lactobacillus reuteri (DSM 17938) in infant colic is somewhat controversial and hence, we designed this study to evaluate its efficacy in infantile colic.
View Article and Find Full Text PDF[Association study of brain-derived neurotrophic factor Val66Met polymorphism and clinical characteristics of first episode schizophrenia].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
April 2012
Objective: To assess the association between brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism and clinical characteristics of first episode schizophrenia in a Chinese Han population.
Methods: Genotyping of BDNF Val66Met polymorphism was carried out for 135 schizophrenic patients and 483 healthy controls with TaqMan probe technology. The patients' psychotic symptoms were assessed using the positive and negative syndrome scale (PANSS).