Antibacterial Mechanism of Chitosan-Gentamicin and Its Effect on the Intestinal Flora of Infected with .

To explore the application of chitosan-gentamicin conjugate (CS-GT) in inhibiting (), which is an important pathogen in aquatic animals worldwide, the antimicrobial activity of CS-GT and the effects of a CS-GT dose on the intestine histopathology and intestinal flora of -infected shrimps were explored. The results showed that CS-GT possessed broad-spectrum antibacterial activity, with minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and half inhibitory concentration (IC) of 20.00 ± 0.