Structural Optimization and Performance of a Low-Frequency Double-Shell Type-IV Flexural Hydroacoustic Transducer.

To amplify the displacement of the radiation shell, a double-shell type-IV curved hydroacoustic transducer was proposed. Through Ansys finite element simulation, the vibration modes of the transducer in different stages and the harmonic response characteristics in air and water were studied, and the bandwidth emission of the hydroacoustic transducer was achieved. By optimizing the size of each component, the resonant frequency of the transducer is 740 Hz, the maximum conductivity was 0.

The health and economic burden of ozone pollution on Alzheimer's disease and mild cognitive impairment in China.

Ozone pollution is increasingly recognized as a serious environmental threat that exacerbates dementia risks, including Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI). Amid rapid industrialization, China faces significant air quality challenges. However, there has been a scarcity of detailed studies assessing the health and economic impacts of ozone pollution on these conditions.

The synergistic effects of PM and CO from China's energy consumption.

PM and CO emissions are of the same origin. Under the double pressure of PM and CO emissions reduction, PM and CO synergistic emissions reduction is an available way to achieve PM and carbon reduction. Previous studies had shown that reducing fossil energy consumption could decrease PM and CO emissions.

Combined detection of vitamin D, CRP and TNF-α has high predictive value for osteoporosis in elderly men.

Objective: To observe the predictive value of 25-hydroxyvitamin D3 (25(OH)D3), C-reactive protein (CRP), and tumor necrosis factor-α (TNF-α) levels for osteoporosis in elderly men.

Methods: A retrospective analysis was conducted in 122 elderly male patients that were tested in The Affiliated Hospital of Xinyang Vocational and Technical College between January 2020 and May 2022. The patients were divided into an osteoporosis group (OG, n = 77) and a control group (CG, n = 45) according to the results of bone mineral density.

Zebrafish Embryos Display Characteristic Bioelectric Signals during Early Development.

Bioelectricity is defined as endogenous electrical signaling mediated by the dynamic distribution of charged molecules. Recently, increasing evidence has revealed that cellular bioelectric signaling is critical for regulating embryonic development, regeneration, and congenital diseases. However, systematic real-time dynamic electrical activity monitoring of whole organisms has been limited, mainly due to the lack of a suitable model system and voltage measurement tools for biology.

MPAI-Ligand Accelerated Pd-Catalyzed C()-H Arylation of Free Aliphatic Acids.

Here, we report the development of a class of bifunctional monoprotected amino-imidazoline (MPAI) ligands and their applications in Pd-catalyzed C()-H arylation of free aliphatic acids. The newly developed MPAI ligand allows the use of 1.0 equiv of aliphatic acids containing an alpha hydrogen for the first time.

Analysis of levels and Clinical value of CA19-9, NLR and SIRI in patients with Pancreatic Cancer with different Clinical Features.

This study aimed to investigate the levels of cancer antigen 19-9 (CA19-9), neutrophil/lymphocyte ratio (NLR) and systemic immune-inflammatory index (SIRI) in patients with pancreatic cancer with different clinical features and their clinical value. For this purpose, 78 patients with pancreatic cancer treated in our hospital from January 2018 to January 2021 were divided into two groups according to the NLR and SIRI calculated by blood routine and biochemical examination before operation. To observe and analyze the relationship between serum CA19-19 levels, clinical features and NLR and SIRI values in patients with different clinical stages and tumor diameter, and the diagnostic value of CA19-9, NLR and SIRI in pancreatic cancer.

Aging and Light Stress Result in Overlapping and Unique Gene Expression Changes in Photoreceptors.

Advanced age is one of the leading risk factors for vision loss and eye disease. Photoreceptors are the primary sensory neurons of the eye. The extended photoreceptor cell lifespan, in addition to its high metabolic needs due to phototransduction, makes it critical for these neurons to continually respond to the stresses associated with aging by mounting an appropriate gene expression response.

The economic loss of public health from PM pollution in the Fenwei Plain.

At present, the concentration of PM in the Fenwei Plain has become the second highest in China, ranking second to the Beijing-Tianjin-Hebei region. At the same time, China began to monitor and control the PM concentration in the Fenwei Plain, but the data indicated that the concentration of PM in the Fenwei Plain rose instead of falling. PM concentrations in 6 cities from the Fenwei Plain ranked highest among the 20 cities in 2018 in China, and PM pollution can cause some health economic loss.

Public health effect and its economics loss of PM pollution from coal consumption in China.

China's energy structure is based on coal resource and it accounts for main proportion in the primary energy consumption. Coal consumption produces PM pollution, which seriously affects public health. Considering that there are few studies on the effect PM pollution produced by coal consumption, this paper uses the Poisson Regression model to estimate the impacts on public health and the economic loss of PM pollution produced by coal consumption using the data in 2015.

Role of mammary serine protease inhibitor on the inflammatory response in oral lichen planus.

Objectives: Oral lichen planus (OLP) is a chronic inflammatory condition with an unclear pathological mechanism. IκB kinase α (IKKα)-regulated mammary serine protease inhibitor (MASPIN) has been shown to mediate inflammation, particularly in cancers. Here, we explored the expression of MASPIN in OLP and its role in the inflammatory response.