Adapting distribution patterns of desert locusts, in response to global climate change.

The desert locust () is a destructive migratory pest, posing great threat to over 60 countries globally. In the backdrop of climate change, the habitat suitability of desert locusts is poised to undergo alterations. Hence, investigating the shifting dynamics of desert locust habitats holds profound significance in ensuring global agricultural resilience and food security.

Protective effect of puerarin in diabetic nephropathy: A systematic review and meta-analysis of animal studies.

Background: Puerarin is a crucial constituent separated from the Chinese herbaceous plant, Pueraria lobata (Willd.) Ohwi, which exhibits multiple biological activities. Previous studies have indicated that puerarin has a function to alleviate renal damage in animal models of diabetic nephropathy (DN).

Cryo-EM structure of Nipah virus L-P polymerase complex.

Nipah virus (NiV) is a non-segmented, negative-strand (NNS) RNA virus, belonging to Paramyxoviridae. The RNA polymerase complex, composed of large (L) protein and tetrameric phosphoprotein (P), is responsible for genome transcription and replication by catalyzing NTP polymerization, mRNA capping and cap methylation. Here, we determine the cryo-electron microscopy (cryo-EM) structure of fully bioactive NiV L-P polymerase complex at a resolution of 3.

Revealing the scientific connotation of compatibility of Chinese medicine medica based on self-assembly technology.

Chinese materia medica (CMM) compatibility is one core content in the theory of Traditional Chinese Medicine (TCM), and elaborating the scientific connotation of CMM compatibility is of great significance to promote the modernization of TCM. Self-assembly is the combination of active ingredients into aggregates through non-covalent bonds, such as hydrogen bonding, electrostatic interactions, ionic interactions, and hydrophobic interactions. The complex properties and special structures of CMM components create the basis for self-assembly.

Effects and Action Mode of Oleic Acid and Azone on Release and Penetration Process of Levothyroxine Sodium Patches.

In recent years, there has been a significant increase in the prevalence of thyroid diseases, particularly hypothyroidism. In this study, we investigated the impact and mechanisms of Chemical permeation enhancement(CPE) on transdermal permeation of levothyroxine sodium (L-T4) patches.We found that the combination of oleic acid (OA) and Azone (NZ) yielded the best transdermal permeation effect for L-T4.

Reciprocal inhibition of autophagy and Botrytis cinerea-induced programmed cell death in 'Shine Muscat' grapes.

Botrytis cinerea causes gray mold, decreasing the quality of table grapes. The berry response to B. cinerea infection was explored in present study, focusing on the relationship between presence of autophagy and programmed cell death (PCD).

Advances in tumor microenvironment: Applications and challenges of 3D bioprinting.

The tumor microenvironment (TME) assumes a pivotal role in the treatment of oncological diseases, given its intricate interplay of diverse cellular components and extracellular matrices. This dynamic ecosystem poses a serious challenge to traditional research methods in many ways, such as high research costs, inefficient translation, poor reproducibility, and low modeling success rates. These challenges require the search for more suitable research methods to accurately model the TME, and the emergence of 3D bioprinting technology is transformative and an important complement to these traditional methods to precisely control the distribution of cells, biomolecules, and matrix scaffolds within the TME.

Light-responsive transcription factors VvHYH and VvGATA24 mediate wax terpenoid biosynthesis in Vitis vinifera.

The cuticular wax that covers the surfaces of plants is the first barrier against environmental stresses and increasingly accumulates with light exposure. However, the molecular basis of light-responsive wax biosynthesis remains elusive. In grape (Vitis vinifera), light exposure resulted in higher wax terpenoid content and lower decay and abscission rates than controls kept in darkness.

Causal role of immune cells in major depressive disorder and bipolar disorder: Mendelian randomization (MR) study.

Background: Major depressive disorder (MDD) and bipolar disorder (BD) are prevalent psychiatric conditions linked to inflammatory processes. However, it is unclear whether associations of immune cells with these disorders are likely to be causal.

Methods: We used two-sample Mendelian randomization (MR) approach to investigate the relationship between 731 immune cells and the risk of MDD and BD.

WO boosted hollow Ni nanoreactors for the hydrodeoxygenation of lignin derivatives.

Reasonable design of non-noble metal catalysts with hollow open structure for hydrodeoxygenation (HDO) of lignin derivatives to value-added chemicals is of great significance but challenging. Herein, a novel MOF-derived multilayer hollow sphere coated nickel‑tungsten bimetallic catalyst (Ni-WO@CN-700) was fabricated via by confined pyrolysis strategy using bimetallic MOFs as a self-sacrificial template, which exhibits robust activity for the typical model HDO of vanillin to 2-methoxy-4-methylphenol (Yield of 100 % at 140 °C for no less than 10 cycles). The characterizations revealed that WO facilitated the dispersion of Ni nanoparticles and adjusted the acidic capacity of the catalyst through the formed Ni-WO heterojunction.

Impact of Flammulina velutipes polysaccharide on properties and structural changes of pork myofibrillar protein during the gel process in the absence or presence of oxidation.

The present study aimed to investigate the impact of Flammulina velutipes polysaccharide (FVSP) on the rheological properties and structural alterations of myofibrillar protein (MP) and oxidized MP (OMP), utilizing techniques such as rhehometer, fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). In the unoxidized system, the addition of 5.00% FVSP significantly improved (p < 0.

Eddy Current Identification Methods and Applications in the Chemical Industry: A Mini-Review.

As one of the most common fluid patterns in the fluid flow process of chemical production, a vortex has been successfully demonstrated to be a structure that promotes interphase mixing and enhances heat and mass transfer. Therefore, it is essential to reveal the vortex evolution laws in order to realize more efficient and less energy-consuming chemical production. In this Mini-Review, the vortex identification criteria are introduced in detail and categorized according to their development history.

Hydrodeoxygenation of furfural to 2-methylfuran over Cu-Co confined by hollow carbon cage catalyst enhanced by optimized charge transfer and alloy structure.

Hydrodeoxygenation of furfural over non-noble metal catalyst is an effective route to synthesis 2-methylfuran, but the reaction is often hampered by the low activity and selectivity of the catalyst. Herein, a bimetallic catalyst with CuCo alloy encapsulated in a hollow nitrogen-doped carbon cages (CuCo/NC) are fabricated by using ZIF-67 as a sacrificial template, which exhibited superior catalytic performance and a full conversion of furfural with a 95.7 % selectivity towards 2-methylfuran was achieved at an under relatively mild reaction conditions (150 ℃, 1.

The Protection of Quinoa Protein on the Quality of Pork Patties during Freeze-Thaw Cycles: Physicochemical Properties, Sensory Quality and Protein Oxidative.

The present study investigated the impact of quinoa protein (QP) on the physicochemical properties, sensory quality, and oxidative stability of myofibrillar protein (MP) in pork patties during five freeze-thaw (F-T) cycles. It was observed that repeated F-T cycles resulted in a deterioration of pork patty quality; however, the incorporation of QP effectively mitigated these changes. Throughout the F-T cycles, the sensory quality of the QP-treated group consistently surpassed that of the control group.

Zishen Yutai pills restore fertility in premature ovarian failure through regulating arachidonic acid metabolism and the ATK pathway.

Ethnopharmacological Relevance: The Zishen Yutai pills (ZYP), a Chinese medicinal formulation derived from the Qing Dynasty prescription "Shou Tai pills", have been documented to exhibit beneficial effects in clinical observations treating premature ovarian failure (POF). However, the anti-POF effects and its comprehensive systemic mechanism have not yet been clarified.

Aim Of The Review: Therapeutic effects and systemic mechanism of ZYP in POF were evaluated.

A critical signal for phenotype transition driven by negative feedback loops.

The biological rhythms governed by negative feedback loops have undergone extensive investigation. However, developing reliable and versatile warning signals to predict periodic fluctuations in physiological processes and behaviors associated with these rhythms remains a challenge. Here, we monitored the heart rate and tracked ovulation dates of 91 fertile women.

CFD Simulation Investigation on the Flow Field Distribution Pattern under Different Operating Environment Pressures in a Jet Impingement-Negative Pressure Reactor.

A jet impingement-negative pressure deamination reactor (JI-NPDR) has excellent ammonia removal efficiency. The CFD numerical simulation method based on the Euler-Euler model and the realizable -ε turbulence model was used to investigate the effect of different negative pressures at the reactor top outlet on the distribution pattern of pressure, velocity, turbulent kinetic energy, and vortex. The results indicate that the overall water flow distribution in the reactor increases in axial cohesion with the increase in negative pressure.

A new cytotoxic disaccharide glycoside from the tubers of .

A new disaccharide glycoside, franchoside A (), and 17 known compounds were isolated from the tubers of Engler. The chemical structure of the previously undescribed compound was elucidated on the basis of detailed spectroscopic analyses. Compounds , , , , and showed significant cytotoxic activities at varying IC values in the range of 4.

Alternative Splicing Factor Heterogeneous Nuclear Ribonucleoprotein U as a Promising Biomarker for Gastric Cancer Risk and Prognosis with Tumor-Promoting Properties.

Gastric cancer (GC) is a major global health concern with poor outcomes. Heterogeneous nuclear ribonucleoprotein U (HNRNPU) is a multifunctional protein that participates in pre-mRNA packaging, alternative splicing regulation, and chromatin remodeling. Its potential role in GC remains unclear.

Liquid chromatography-tandem mass spectrometry analysis of a ratio-optimized drug pair of Aiton and Franch and study on the mechanism of anti-colorectal cancer effect of two alkaloids thereof.

The drug pair consisting of Aiton (, Kushen) and Franch. (, Huanglian), as described in Prescriptions for Universal Relief (Pujifang), is widely used to treat laxation. Matrine and berberine are the major active components of Kushen and Huanglian, respectively.

In situ construction of 3D NiMo bimetallic catalysts anchored on dendritic mesoporous silica for the upgrading of biomass derivatives.

Reasonable construction of bi-function catalysts with well dispersed hydrogenation active sites and acidic sites are crucial for the hydrodeoxygenation (HDO) of biomass-derived compounds but still a huge challenge. Herein, a 3D Mo functionalized Ni-based bimetallic embedded catalyst with fine metal nanoparticles size (<6 nm) was prepared for the first time using dendritic mesoporous silica as a sacrificial template by one-pot hydrothermal synthesis and adopted in the HDO process of vanillin (VAN) upgrade to 2-methoxy-4-methylphenol (MMP). The characterization results illustrated that Mo species regulated the acidity of the catalyst and promoted the formation of Ni-Mo alloy sites.

Migration risk of fall armyworm () from North Africa to Southern Europe.

With the development of globalization and agriculture trade, as well as its own strong migratory capacity, fall armyworm (FAW) () (J.E. Smith) has invaded more than 70 countries, posing a serious threat to the production of major crops in these areas.