A chemical investigation of Streptomyces sp. GZWMJZ-662, an endophytic actinomycete isolated from Houttuynia cordata Thunb., has yielded eleven bohemamine dimers (1-11).
View Article and Find Full Text PDF"Brain fog," a persistent cognitive impairment syndrome, stands out as a significant neurological aftermath of coronavirus disease 2019 (COVID-19). Yet, the underlying mechanisms by which COVID-19 induces cognitive deficits remain elusive. In our study, we observed an upregulation in the expression of genes linked to the inflammatory response and oxidative stress, whereas genes associated with cognitive function were downregulated in the brains of patients infected with COVID-19.
View Article and Find Full Text PDFIntroduction: Postmenopausal osteoporosis (PMOP) is a common chronic disease, and the loss of bone density and bone strength after menopause are its main symptoms. Effective treatments for PMOP are still uncertain, but Chinese medicine has some advantages in slowing down bone loss. Shengu granules are often used clinically to treat PMOP.
View Article and Find Full Text PDFWe propose a scheme to generate nonreciprocal photon blockade in a stationary whispering gallery microresonator system based on two physical mechanisms. One of the two mechanisms is inspired by recent work [Phys. Rev.
View Article and Find Full Text PDFIn the dispersive limit, the conventional photon blockade effect cannot be realized due to the absence of photon nonlinearity. We propose a scheme to recover the photon blockade effect of the dispersive Tavis-Cummings model, which makes it possible to realize the conventional photon blockade effect in the dispersive limit. It is shown that both single-photon and two-photon blockade effects can be recovered at appropriate qubit driving strength.
View Article and Find Full Text PDFInjury to the anterior talofibular ligament (ATFL) is a common acute injury of the lateral foot ligament. Untimely and improper treatment significantly affects the quality of life and rehabilitation progress of patients. The purpose of this paper is to review the anatomy and the current methods of diagnosis and treatment of acute injury to the ATFL.
View Article and Find Full Text PDFAchalasia cardia, type of esophageal dynamic disorder, is a relatively rare primary motor esophageal disease characterized by the functional loss of plexus ganglion cells in the distal esophagus and lower esophageal sphincter. Loss of function of the distal and lower esophageal sphincter ganglion cells is the main cause of achalasia cardia, and is more likely to occur in the elderly. Histological changes in the esophageal mucosa are considered pathogenic; however, studies have found that inflammation and genetic changes at the molecular level may also cause achalasia cardia, resulting in dysphagia, reflux, aspiration, retrosternal pain, and weight loss.
View Article and Find Full Text PDFBackground: Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and long-lasting side effect caused by various anticancer agents that damage sensory, motor and autonomic nerves. It can cause maladaptive behaviors, including disease severity, anxiety, depression, sleep disorders, falls, and social impairment. These disorders have physical, psychological and social effects on patients and can seriously influence their quality of life.
View Article and Find Full Text PDFBackground: Stroke has a great influence on the patient's mental health, and reasonable psychological adjustment and disease perception can promote the recovery of mental health.
Aim: To explore the relationships among resilience, coping style, and uncertainty in illness of stroke patients.
Methods: A retrospective study was used to investigate 154 stroke patients who were diagnosed and treated at eight medical institutes in Henan province, China from October to December 2019.
Introduction: The aim of this study is to rigorously review the efficacy and safety of olanzapine in chemotherapy-induced nausea and vomiting (CINV) settings including (1) at 5- and 10-mg doses, and (2) the setting of highly emetogenic chemotherapy (HEC) and moderately emetogenic chemotherapy (MEC).
Methods: Embase, Pubmed, and Cochrane Library were searched from the establishment of the database through April 18, 2021. The primary efficacy endpoints were the rate of complete response (CR; no emesis and no rescue), in the acute (0-24 h post-chemotherapy), delayed (24-120 h post-chemotherapy), and overall (0-120 h post-chemotherapy) phases.
We propose a scheme to generate squeezed states of magnon and phonon modes and verify squeezing transfer between different modes of distinct frequencies in a cavity magnomechanical system which is composed of a microwave cavity and a yttrium iron garnet sphere. We present that by activating the magnetostrictive force in the ferrimagnet, realized by driving the magnon mode with red-detuned and blue-detuned microwave fields, the driven magnon mode can be prepared in a squeezed state. Moreover, the squeezing can be transferred to the cavity mode via the cavity-magnon beamsplitter interaction with strong magnomechanical coupling.
View Article and Find Full Text PDFThe dissipative squeezing mechanism is an effective method to generate the strong squeezing, which is important in the precision metrology. Here, we propose a practical method to achieve arbitrary bosonic squeezing via introducing frequency modulation into the coupled harmonic resonator model. We analyze the effect of frequency modulation and give the analytical and numerical squeezing results, respectively.
View Article and Find Full Text PDFWe propose a scheme to enhance the single- and two-photon blockade effects significantly in a nonlinear hybrid optomechanical system with optical parametric amplification (OPA). The scheme does not rely on strong single-photon optomechanical coupling and can eliminate the disadvantages of suppressing multi-photon excitation incompletely. Through analyzing the single-photon blockade (1PB) mechanism and optimizing the system parameters, we obtain a perfect 1PB with a high occupancy probability of single-photon excitation, which means that a high-quality and efficient single-photon source can be generated.
View Article and Find Full Text PDFSemi-alicyclic colorless and transparent polyimide (CPI) films usually suffer from the high linear coefficients of thermal expansion (CTEs) due to the intrinsic thermo-sensitive alicyclic segments in the polymers. A series of semi-alicyclic CPI films containing rigid-rod amide moieties were successfully prepared in the current work in order to reduce the CTEs of the CPI films while maintaining their original optical transparency and solution-processability. For this purpose, two alicyclic dianhydrides, hydrogenated pyromellitic anhydride (HPMDA, I), and hydrogenated 3,3',4,4'-biphenyltetracarboxylic dianhydride (HBPDA, II) were polymerized with two amide-bridged aromatic diamines, 2-methyl-4,4'-diaminobenzanilide (MeDABA, a) and 2-chloro-4,4'-diaminobenzanilide (ClDABA, b) respectively to afford four CPI resins.
View Article and Find Full Text PDFWe present a proposal to generate robust optomechanical entanglement induced by the blue-detuning laser and the mechanical gain in a double-cavity optomechanical system. We show that the stability of the system can be obtained by introducing a cavity mode driven by the red-detuning laser in the blue-detuning regime. In contrast to the red-detuning regime, we find that the entanglement in the blue-detuning regime is extremely robust to temperature.
View Article and Find Full Text PDFIn this article, two kinds of complex dynamical networks (CDNs) with state and derivative coupling are investigated, respectively. First, some important concepts about finite-time passivity (FTP), finite-time output strict passivity, and finite-time input strict passivity are introduced. By making use of state-feedback controllers and adaptive state-feedback controllers, several sufficient conditions are given to guarantee the FTP of these two network models.
View Article and Find Full Text PDFWe present a scheme for the electromagnetically induced transparency (EIT)-like nonlinear ground-state cooling in a double-cavity optomechanical system in which an optical cavity mode is coupled parametrically to the square of the position of a mechanical oscillator, an additional auxiliary cavity is coupled to the optomechanical cavity. The optimum cooling conditions is derived, based on which the heating process can be well suppressed and the mechanical resonator can be cooled with an optimal effect to near its ground state through EIT-like cooling mechanism even in unresolved sideband regime. It is demonstrated by numerical simulations that not only the average phonon number of steady state is lower than that of single-cavity optomechanical system, but also the cooling rate is greatly faster than that of the linear optomechanical coupling due to the two-phonon cooling process in the quadratic coupling.
View Article and Find Full Text PDFIn this paper, the output synchronization problem for complex dynamical networks (CDNs) with multiple output or output derivative couplings is discussed in detail. Under the help of Lyapunov functional and inequality techniques, an output synchronization criterion is presented for CDNs with multiple output couplings (CDNMOCs). To ensure the output synchronization of CDNMOCs, an adaptive control scheme is also devised.
View Article and Find Full Text PDFExperimental realization of the Kitaev model is a greatly attractive topic due to the potential applications to build robust qubits against decoherence in topological quantum computation. In this work, we investigate the charged whispering-gallery microcavity array model and simulate the normal Kitaev chain under this mechanism in the first time. We find that the system reveals profound connections with the normal Kitaev chain and its some derivatives, and the topological property of the system depends on effective optomechanical coupling strength deeply.
View Article and Find Full Text PDFA scheme is proposed to cool a rotating mirror close to its ground state in a double-Laguerre-Gaussian-cavity optomechanical system, where an auxiliary cavity and a two-level atomic ensemble simultaneously couple to the original optomechanical cavity. By choosing parameters reasonably, we find that the cooling process of the rotating mirror can be strengthened greatly while the heating process can be suppressed effectively. We show that the proposed ground-state cooling scheme can work well no matter whether in the weak or strong coupling regime for the atomic ensemble and original cavity.
View Article and Find Full Text PDFWe propose a scheme to show that the system consisting of two macroscopic oscillators separated in space which are coupled through Coulomb interaction displays the classical-to-quantum transition behavior under the action of optomechanical coupling interaction. Once the optomechanical coupling interaction disappears, the entanglement between the two separated oscillators disappears accordingly and the system will return to classical world even though there exists sufficiently strong Coulomb coupling between the oscillators. In addition, resorting to the squeezing of the cavity field generated by an optical parametric amplifier inside the cavity, we discuss the effect of squeezed light driving on this classical-to-quantum transition behavior instead of injecting the squeezed field directly.
View Article and Find Full Text PDFWe study the physical properties of double-cavity optomechanical system in which the mechanical resonator interacts with one of the coupled cavities and another cavity is used as an auxiliary cavity. The model can be expected to achieve the strong optomechanical coupling strength and overcome the optomechanical cavity decay, simultaneously. Through the coherent auxiliary cavity interferences, the steady-state squeezing of mechanical resonator can be generated in highly unresolved sideband regime.
View Article and Find Full Text PDFWe propose a scheme for the creation of robust entanglement between a movable mirror and atomic ensemble at the macroscopic level in coupled optomechanical system. We numerically simulate the degree of entanglement of the bipartite macroscopic entanglement and show that it depends on the coupling strength between the cavities and is robust with respect to the certain environment temperature. Inspiringly and surprisingly, according to the reported relation between the mechanical damping rate and the mechanical frequency of the movable mirror, the numerical simulation result shows that such bipartite macroscopic entanglement persists for environment temperature up to 170 K, which breaks the liquid nitrogen cooling and liquid helium cooling and largely lowers down the experiment cost.
View Article and Find Full Text PDF