Publications by authors named "Dong Tao Shi"

Article Synopsis
  • A multicenter randomized controlled trial compared the effectiveness of over-the-scope clips (OTSCs) and standard endoscopic treatments for controlling acute nonvariceal bleeding in the upper gastrointestinal tract, involving 190 adult patients.
  • Results showed that the 30-day probability of further bleeding was significantly lower in the OTSC group (3.2%) compared to the standard treatment group (14.6%), indicating that OTSCs may be more effective.
  • Additionally, OTSCs led to fewer failures in controlling bleeding, lower rates of recurrent bleeding, and reduced needs for further interventions, suggesting they could be a beneficial first-line treatment option.
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Objective: A submucosal injection is usually required to improve the efficacy and safety of endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR). This study aimed to evaluate the performance of 3.3% sodium carboxymethyl starch (Na-CMS) solution, a novel submucosal injection solution, for ESD and EMR.

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BLU is a candidate tumor suppressor gene, which is epigenetically inactivated in many human malignancies. However, the expression and biological functions of BLU in gastric cancer has not yet been reported. In the present study, we identified a functional BLU promoter which was regulated by the transcription activator Sp1.

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Ras-association domain family 1A (RASSF1A), a candidate tumor suppressor gene, is frequently silenced and inactivated by hypermethylation of its promoter region in several human tumors. However, the association between RASSF1A promoter methylation and gastric cancer risk remains conflicting. The aim of this study was to assess the association of RASSF1A promoter methylation with gastric cancer risk by a comprehensive meta-analysis.

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