Expression profile of tumor endothelial marker 7 and a putative ligand in the rat spinal cord and dorsal root ganglion.

Study Design: To analyze the expression profile of tumor endothelial marker 7 (TEM7) in the spinal cord and dorsal root ganglion (DRG).

Purpose: To investigate the expression profile of TEM7 in the spinal cord and DRG of adult and developing rats.

Overview Of Literature: Tumor endothelial marker 7 (TEM7) is a putative transmembrane protein that is highly expressed in the tumor endothelium and in cerebellar neurons.

Expression of tumor endothelial marker 7 mRNA and protein in the dorsal root ganglion neurons of the rat.

Tumor endothelial marker7 (TEM7) is a transmembrane protein that is highly expressed in the tumor endothelium and neurons. In the present study, the expression profile of TEM7 mRNA and protein was investigated in the dorsal root ganglion (DRG) of the rats. In situ hybridization and reverse transcription polymerase chain reaction studies revealed that TEM7 mRNA expression was localized to the neuronal population of the sensory ganglion.