Synergistic effect evaluation method of atmospheric emission reduction based on deep learning fusion model.

Currently, the absence of a nonlinear response between air quality and industrial emissions, which accurately captures the complex relationship between pollution levels and emission sources, poses a significant challenge in the formulation of effective control policies. For the purpose of effectively managing industrial emissions and mitigating severe pollution peaks, a new method for evaluating the synergistic effects of atmospheric emission reduction was proposed. The objective of this method is to simulate the impact of emissions on air quality.

[Predicting Ozone Concentration in Hangzhou with the Fusion Class Stacking Algorithm].

Aiming at the problem that the single machine learning model has low prediction accuracy of daily average ozone concentration, an ozone concentration prediction method based on the fusion class Stacking algorithm （FSOP） was proposed, which combined the statistical method ordinary least squares （OLS） with machine learning algorithms and improved the prediction accuracy of the ozone concentration prediction model by integrating the advantages of different learners. Based on the principle of the Stacking algorithm, the observation data of the daily maximum 8h ozone average concentration and meteorological reanalysis data in Hangzhou from January 2017 to December 2022 were used. Firstly, the specific ozone concentration prediction models based on the light gradient boosting machine （LightGBM） algorithm, long short-term memory model （LSTM）, and Informer model were established, respectively.

Quality improvement of nursing on patients with complex cerebral arteriovenous malformation undergoing hybrid surgery: a prospective single-center study.

Background: We sought to explore an optimal clinical nursing mode following a hybrid surgery for cerebral arteriovenous malformation.

Methods: Patients with complex cerebral arteriovenous malformations seen in our neurosurgery department from January 2016 to December 2017 were prospectively enrolled. The hybrid surgery protocol included "angiographic diagnosis, surgical resection, and intraoperative angiographic evaluation" and "angiographic diagnosis and embolization, surgical resection, and intraoperative angiographic evaluation".

[Total nasal reconstruction with total rib cartilage framework].

Objective: To investigate a new technique for nasal reconstruction with total rib cartilage framework.

Methods: The expanded frontal flap was fabricated by skin expansion and flap delay to cover the reconstructed nose. The dorsal flap was reversed as the lining of reconstructed nose.

[Correction of secondary nasal deformity of cleft lip with autogenous costal cartilage framework].

Objective: To investigate the correction of secondary nasal deformity of cleft lip with autogenous costal cartilage framework.

Methods: 237 cases with secondary nasal deformity of unilateral cleft lip were treated. The rib cartilage was harvested through a mini-invasive incision, and was fabricated as a C-shaped framework, as well as some cartilage fragments.

[Closure of cystic cavity-type bedsore by subcutaneous undermining dissection with continuous negative pressure drainage].

Objective: To investigate the clinical effect of subcutaneous undermining dissection with continuous negative pressure drainage for the closure of cystic cavity-type bedsore.

Methods: 12 patients with cystic cavity-type bedsore underwent surgical debridement and the wounds were closed after subcutaneous undermining dissection. The negative pressure drainage was put in the deep space.

Polo-like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation.

Ultraviolet (UV) irradiation can result in cell cycle arrest. The reactivation of Polo-like kinase 1 (Plk1) is necessary for cell cycle reentry. But the mechanism of how Plk1 regulates p53 in UV-induced mitotic arrest cells remained elusive.

[The study on the STAT3 labeled by GFP affecting the migration of BEL-7402 cell line].

Signal transducers and activators of transcription (STATs) are key DNA-binding proteins in JAK/STATs signal pathway. Aberrant expression and activation of STAT3 have been identified in many kinds of tumors. We report here that constitutive activation of STAT3 was present in BEL-7402 cells.

Knockdown of c-Met by adenovirus-delivered small interfering RNA inhibits hepatocellular carcinoma growth in vitro and in vivo.

c-Met is highly expressed and constitutively activated in various human tumors. We employed adenovirus-mediated RNA interference technique to knock down c-Met expression in hepatocellular carcinoma cells and observed its effects on hepatocellular carcinoma cell growth in vitro and in vivo. Among the five hepatocellular carcinoma and one normal human liver cell lines we analyzed, c-Met was highly expressed and constitutively tyrosine phosphorylated in only MHCC97-L and HCCLM3 hepatocellular carcinoma cells.

[Study on the role of calcium signal during mature resumption of isolated mouse germinal vesicles in a cell free system].

A cell-free system including HeLa cell lysate of synchronized metaphase or G2-phase and isolated germinal vesicles (GV) from mouse oocytes was used to study the role of calcium and its downstream mediator during mature resumption. The isolated GVs could resume meiotic maturation in the lysate prepared from M phase HeLa cell, which marked by chromatin condensation. And this process was not affected by calcium chelating agent.

The association of calmodulin with central spindle regulates the initiation of cytokinesis in HeLa cells.

Calmodulin is a major cytoplasmic calcium receptor that performs multiple functions in the cell including cytokinesis. Central spindle appears between separating chromatin masses after metaphase-anaphase transition. The interaction of microtubules from central spindle with cell cortex regulates the cleavage furrow formation.

hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation.

hNRAGE, a neurotrophin receptor p75 interacting MAGE homologue, is cloned from a human placenta cDNA library. hNRAGE can inhibit the colony formation of and arrest cell proliferation at the G1/S and G2/M stages in hNRAGE overexpressing cells. Interestingly, hNRAGE also increases the p53 protein level as well as its phosphorylation (Ser392).

Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402.

Wnt signaling pathway is essential for development and tumorigenesis, however, this signaling pathway in the progress of hepatocellular carcinoma (HCC) remains unclear. In this paper, we studied the function of human T-cell transcription factor-4 (TCF4), a key factor of Wnt signaling pathway, on the proliferation of HCC cell line. We showed that the expression of TCF4 mRNA in HCC cell line BEL-7402 was higher than that in immortalized normal liver cell line L02.

[The distribution of calmodulin with midbody and its involvement in cytokinesis regulation].

Calmodulin (CaM) is a major cytoplasmic Ca2+ receptor and performs a multiplicity of functions in the cell. By using GFP-CaM fusion protein, we have studied the detailed dynamic redistribution of CaM during cytokinesis in HeLa cells. CaM associates with midbody in late cytokinesis phase.