The effect of minocycline on motor neuron recovery and neuropathic pain in a rat model of spinal cord injury.

Objective: Minocycline, a second-generation tetracycline-class antibiotic, has been well established to exert a neuroprotective effect in animal models and neurodegenerative disease through the inhibition of microglia. Here, we investigated the effects of minocycline on motor recovery and neuropathic pain in a rat model of spinal cord injury.

Methods: To simulate spinal cord injury, the rats' spinal cords were hemisected at the 10th thoracic level (T10).

Upward migration of distal ventriculoperitoneal shunt catheter into the heart: case report.

Ventriculoperitoneal (VP) shunt is commonly and effectively used to treat hydrocephalus. Intracardiac migration of the shunt catheter is a rare complication. A 68-year-old woman underwent ventriculoperitoneal shunting for hydrocephalus secondary to subarachnoid hemorrhage due to anterior communicating artery aneurysm rupture.

Recurrent metastatic hepatocellular carcinoma presenting as consecutive "mirror image" intracerebral haematomas.

A 34-year old man with a past history of hepatocellular carcinoma (HCC) complained of headache and visual disturbance. Neuroimaging revealed a right occipital haematoma with rim enhancement and at operation, a metastasis from the primary malignancy was found. Five months after surgery and subsequent adjuvant therapy, he presented with blindness.