Use of a p64 MW Flow Diverter with Hydrophilic Polymer Coating (HPC) and Prasugrel Single Antiplatelet Therapy for the Treatment of Unruptured Anterior Circulation Aneurysms: Safety Data and Short-term Occlusion Rates.

Purpose: To assess the safety and short-term occlusion rates in procedures using the p64 MW hydrophilic polymer-coated (HPC) flow diverter (FD) with prasugrel single antiplatelet therapy (SAPT) for the treatment of anterior circulation saccular aneurysms.

Methods: We retrospectively identified patients who underwent treatment of one or more intracranial anterior circulation saccular aneurysms between March 2020 and December 2021 with a p64 MW HPC FD and prasugrel SAPT with verified P2Y12 platelet receptor inhibition. Patients diagnosed with fusiform, dissecting, or recently ruptured aneurysms were excluded.

[Prolonged weaning during early neurological and neurosurgical rehabilitation : S2k guideline published by the Weaning Committee of the German Neurorehabilitation Society (DGNR)].

Prolonged weaning of patients with neurological or neurosurgery disorders is associated with specific characteristics, which are taken into account by the German Society for Neurorehabilitation (DGNR) in its own guideline. The current S2k guideline of the German Society for Pneumology and Respiratory Medicine is referred to explicitly with regard to definitions (e.g.

Novel immunogenic antigens increase classification accuracy in meningioma to 93.84%.

There is growing evidence that simultaneous analysis of multiple autoantibody reactions can be utilized for diagnosis of neoplasms. Using a set of 57 meningioma-associated antigens, we recently separated meningioma patients from individuals without known disease with an accuracy of 90.3%.

[Dysphagia after ventral spondylodesis].

Background: Complications caused by osteosynthetic material after cervical spine surgery are rare.

Patient And Method: The case of a 36-year-old patient is reported, who suffered the extrusion of a screw and migration through the hypopharynx after ventral spondylodesis of a cervical spine fracture.

Result: Dysphagia occurred shortly after spinal surgery.

In vitro and in vivo metabolism of the soy isoflavone glycitein.

Glycitein (GLY) is a major isoflavone of soy germ which is used as a functional ingredient to enrich foods with isoflavones as well as a component of soy supplements. Since data on the metabolism of GLY are incomplete, the in vitro phase I metabolism of GLY using rat liver microsomes, human liver microsomes (HLM), as well as human fecal flora was investigated. Furthermore, the in vivo metabolism has been studied after administration of GLY to Sprague-Dawley rats.

[Treatment of atrial fibrillation with intraoperative radiofrequency ablation in one stage with valvular surgery].

Atrial fibrillation is the most frequent chronic arrhythmia, with significant cardiovascular morbidity and mortality risk. Poor remission rate with medical treatment and the outstanding efficacy of Cox-maze procedure inspired the less invasive intraoperative radiofrequency ablation therapy in patients undergoing open heart surgery. In June 2003 the first maze procedure in Hungary with the Medtronic Cardioblate surgical ablation system, with mitral and tricuspid valvuloplasty in a patient suffering from mitral and tricuspid insufficiency with paroxysmal atrial fibrillation, was performed in our institution.

Prospective comparative study of the effectiveness of epidural morphine and ropivacaine for management of pain after spinal operations.

Objective: Evaluation of the effectiveness of local application of morphine or ropivacaine for treatment of local and radicular pain after lumbar disc operations. Critical review of the literature about the possibilities of management of postoperative pain after spinal operations.

Methods: A total of 113 patients were randomly given 5 mg morphine sulfate (N=42), 10 ml 0,25% ropivacaine (N=42) or physiological NaCl solution (N=21) locally after lumbar disc operation before wound closure.

Prognostic value of SSEP in early aneurysm surgery after SAH in poor-grade patients.

We evaluate the prognostic value of somatosensory evoked potentials (SSEP) in poor-grade patients after early surgery for aneurysmal subarachnoid hemorrhage compared to the Hunt and Hess (H&H) and WFNS scales. Ninety patients with angiographically proven aneurysms graded H&H IV or V were evaluated retrospectively. The aneurysms of 72 patients were clipped.

[Symptomatic Langerhans-cell-histiocytosis of the cervical spine in a child: case report].

We report on a six year old female presented with a painful torticollis and a hemidysaesthesia caused by destruction of the third cervical vertebra and a paravertebral soft-tissue mass. At diagnostic routine finally a biopsy gives the diagnosis of Langerhans cell histiocytosis. In a second open approach the destructed vertebral body was replaced by a precisely adjusted autologous bone interponate and the patient was maintained in halo vest immobilisation.

[Subarachnoid hemorrhage from the anterior communication artery in a sex offender. Considerations regarding liability].

A 32-year-old man was accused of attempted rape. While urinating at the side of the road he felt an erection. He approached a 9-year-old girl who happened to be coming along and pressed his penis between her legs until ejaculation.

Microsurgery of cerebral lesions under stereotactic conditions.

Microsurgical excision of cerebral lesions was carried out under CT-guided stereotactic conditions. For lesions located in critical cortical areas, cerebral teleangiography under stereotactic conditions provided the coordinates of the vascular elements related to the structures and adjacent to the lesion without X-ray distortion. Small size cortical and subcortical lesions were targeted using the stereotactic biopsy probe as a guide.

[Effect of recombinant human erythropoietin on autologous blood donation for heart surgery].

Pharmacological stimulation of erythropoiesis was studied in patients selected for open heart surgery, and undergoing a programme of autologous blood predonation prior to surgery. Sixteen patients (group I: ery) received 4000 I. U.

[Neuroradiologic diagnosis of intracranial epidermoid tumors].

Intracranial epidermoids are primarily extracerebral congenital cysts. Intra- and extradural types are differentiated: intradural lesions originate in the intracranial CSF spaces, and extradural lesions in the bony skull. Epidermoids increase in size passively as the result of an increase in the cyst volume and not because of active growth.

Premature craniosynostosis. A retrospective analysis of a series of 52 cases.

A retrospective analysis of a consecutive series of 52 cases with premature craniosynostosis is presented. Excellent functional, cosmetic, and social results could be achieved by resection of prematurely fused sutures and the creation of artificial growth sutures. Pronounced skull deformities have been corrected using the "basket handle", the "visor plasty", and the "T- bone" techniques or a combination of several of these skull form correction techniques.

Prognostic factors in the treatment of cerebellar haemorrhage.

A prospective study for the treatment of cerebellar haemorrhage was conducted in a non-selected group of 33 patients. All patients with cerebellar haemorrhage arriving at the Department of Neurosurgery at Homburg/Saar have been included in this study, also those in bad condition, with high risk factors, and the aged. All of them required intensive care respectively intensive supervision.

Syringomyelia: a brief review of ontogenetic, experimental and clinical aspects.

The generally accepted definition of syringomyelia is that it is a chronically progressive illness characterized by the presence of cavities or syrinxes in the spinal cord. As manifold as the terminology of syringomyelia are the hypotheses of the etiology. Nowadays with MRI without and with gadolinium it is possible to recognize intramedullar cavities safely, the MR especially the cine-MR provides information on pathophysiological details of the flow and intracavitary pressure dependent pulsations of the CSF.

T-bone plastique for treatment of brachy-turricephaly.

The "T-Bone Plastique", which is presented in this paper, allows a surgical correction even of extreme cases of brachy-turricephaly together with malformations of the occipital region in one operative session. Brachy-turricephaly is characterized by abnormal vertical height of the skull and a shortening of its anterior-posterior length, frequently combined with malformations of the occipital region. Resection of the prematurely closed coronal suture, bi-parietal trepanations with 90 degrees rotation and side-exchange of the parietal bone flaps, double transverse trepanation of the occipital bone and outward bending and shifting of the bone fragments enable a bony remodeling and normalization of the deformed skull.

Intraventricular haemorrhage caused by aneurysms and angiomas.

More than 200 intraventricular haematomas (IVH) have been treated in the Homburg Neurosurgical University Clinic since computed tomography was available and facilitated the diagnosis. Among 200 consecutive cases, which are analysed and presented in this publication, there were 71 patients with subarachnoid haemorrhage (SAH)--58 of whom with angiographically and/or pathologically verified aneurysms--, and 21 cases with intraventricular angiomas. IVH without concomitant intracerebral haematoma (ICH) and without evidence of SAH is highly suggestive of intraventricular angioma.

[The use of personal computers for the collection, storage and analysis of data from neurosurgical intensive care monitoring].

For data acquisition intensive care neurosurgery increasingly has recourse to modern electronics, which have become an integral part of many aspects of present-day neurosurgery. Despite their high technical standard, the devices in common use often lack flexibility. Their range of possible applications is defined by the manufacturer, and the user has little or no influence on them.

[Aneurysms as a rare cause of chronic subdural hematomas].

Chronic subdural haematomas are nowadays usually diagnosed via computed tomography. Followups are also by this method. It is therefore inevitable that aneurysms or other vascular malformations are overlooked as rare but important causes of such haematomas.