Publications by authors named "Donatien De Marignan"
Article Synopsis
- - The study compared mortality rates and patient burden among adult ICU patients with respiratory failure due to RSV, COVID-19, seasonal influenza, and H1N1, involving a total of 807 patients.
- - Patients with RSV had more comorbidities, while those with COVID-19 presented with less severe conditions at admission, indicated by lower SAPS-II and SOFA scores.
- - Results showed that COVID-19 and H1N1 were linked to higher mortality rates compared to RSV, despite patients with RSV being more severely ill, suggesting a better overall outcome for those affected by RSV and seasonal influenza.
Objective: Central pontine myelinolysis (CPM) is a rare demyelinating disease that affects the pons and which can cause extreme disabilities such as locked-in syndrome (LIS) in the initial phase. The aim of the study was to describe the evolution over a 12-month period of two patients with CPM causing an initial LIS.
Method: We retrospectively report the unexpected clinical outcome of these two patients in relation with the anatomical damages documented by brain MRI, associated with diffusion tensor imaging and reconstruction of corticospinal tracts in tractography.
Article Synopsis
- - The study aimed to compare the intrinsic mortality rates and overall burden of COVID-19 versus seasonal influenza pneumonia among ICU patients in Lyon, France, from 2015 to 2021.
- - A total of 350 patients with COVID-19 and 325 with influenza were included, with the analysis focusing on mortality rates at different time intervals after ICU admission.
- - Results indicated that although COVID-19 patients were generally younger and less comorbid, the risk of death for patients with COVID-19 was significantly higher than that for those with seasonal influenza after adjusting for various medical factors.