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Publications by authors named "Donatella Pia Spano"

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Synopsis of recent research by authors named "Donatella Pia Spano"

  • - Donatella Pia Spano's recent research is primarily focused on the role of metalloproteinases, particularly ADAM17 and ADAM15, in ectodomain shedding, a critical process for cell communication and various biological functions.
  • - Her work has included the development of proteomic workflows to identify substrates and regulators of these metalloproteinases, revealing important insights into their specific biological roles and potential therapeutic targets.
  • - Additionally, Spano's research on chondrosarcoma highlights the identification of biomarkers linked to chemical hypoxia, emphasizing the need for improved understanding of the molecular mechanisms and potential therapies for this type of bone tumor.

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