Theories of Arousal Predict a Link Between Heart Rate Variability and Reactive Aggression: Meta-Analytic Results Disagree.

Polyvagal theory posits that habitually aggressive individuals might have an impaired capacity to calm after arousal, which has led to the investigation of Arousal-based biological indicators - "biomarkers" - of aggression, to identify individuals at high risk. The most popular approach in research examining (specifically reactive) aggression is the use of wearable technologies that can non-invasively measure heart rate variability (HRV), a cardiovascular phenomenon impacted by activation of the parasympathetic ("rest and digest") nervous system. But there is a problem: no one has systematically analyzed the results of these studies to determine if HRV is an effective predictor of reactive aggression.

Selinexor in combination with dexamethasone with or without bortezomib in heavily pretreated multiple myeloma: A case series.

This report describes the characteristics and outcomes of 18 heavily pretreated patients with multiple myeloma (MM) who were subsequently treated with selinexor. This is a case series of 18 patients with MM who were treated with selinexor and dexamethasone (Sd) or selinexor, bortezomib, and dexamethasone (SVd) in 12 hospitals in the UK between 2019 and 2021. Eight patients received Sd and 10 patients received SVd.

pH Affects the Spontaneous Formation of HO at the Air-Water Interfaces.

Recent studies have shown that the air-water interface of aqueous microdroplets is a source of OH radicals and hydrogen peroxide in the atmosphere. Several parameters such as droplet size, salt, and organic content have been suggested to play key roles in the formation of these oxidants. In this study, we focus on the effect of acidity on the spontaneous interfacial hydrogen peroxide formation of salt-containing droplets.

Both partners' negative emotion drives aggression during couples' conflict.

Researchers examining conflict between intimate partners believe that the experience and expression of emotion drives aggressive behaviour. Intra-personally, increases in negative affect make aggression more likely. Inter-personally, theoretical models suggest that each individuals' perception of their partners' emotion also influences aggression, potentially creating a Violence Escalation Cycle.

Spontaneous Production of I at the Surface of Aqueous Iodide Solutions.

Several groups have recently reported spontaneous production of atmospherically reactive species, including molecular iodine (I) at the air-water interface of droplets. In this study, glancing angle laser-induced fluorescence spectroscopy was used to track the luminol fluorescence at the surface of sodium iodide (NaI) and sodium chloride (NaCl) solutions. Although luminol fluorescence is hardly quenched by halide anions, even up to fairly high concentrations, it is effectively quenched by I.

Commit to your putting stroke: exploring the impact of quiet eye duration and neural activity on golf putting performance.

Introduction: There is a growing interest in characterizing the cognitive-motor processes that underlie superior performance in highly skilled athletes. The aim of this study was to explore neural markers of putting performance in highly skilled golfers by recording mobile EEG (electroencephalogram) during the pre-shot period.

Methods: Twenty-eight right-handed participants (20 males) with a mean age of 24.

Prognostic value of platelet levels in patients with aneurysmal Subarachnoid Hemorrhage.

Pathophysiological processes following aneurysmal subarachnoid hemorrhage (aSAH) include upregulated underlying systemic inflammation, which is reflected by changes in different peripheral blood cells and their sub-populations. As inflammation is a crucial process that contributes to post-aSAH complications and clincal outcome, blood cell numbers and ratios in systemic circulation may predict the outcome and provide rapid and easy to quantify point of care biomarkers for these critically ill patients. To identify blood-derived cellular inflammatory parameters which allow a precise prediction of patient outcome after aSAH.

Electrophysiologic and cardiovascular manifestations of Duchenne and Becker muscular dystrophies.

There have been significant advances in the diagnosis and management of the hereditary muscular disorders Duchenne and Becker muscular dystrophy (DMD and BMD). Cardiac electrophysiologic and cardiovascular involvement has long been important in the surveillance, care, and prognosis of patients with both BMD and DMD and is the leading cause of mortality in patients with DMD. With improved long-term prognosis, rhythm disorders and progressive cardiomyopathy with resultant heart failure are increasingly common.

Investigating the Brain Mechanisms of Externally Cued Sit-to-Stand Movement in Parkinson's Disease.

Background: One of the more challenging daily-life actions for Parkinson's disease patients is starting to stand from a sitting position. Parkinson's disease patients are known to have difficulty with self-initiated movements and benefit from external cues. However, the brain processes underlying external cueing as an aid remain unknown.

Neural correlates of motor imagery and execution in real-world dynamic behavior: evidence for similarities and differences.

A large body of evidence shows that motor imagery and action execution behaviors result from overlapping neural substrates, even in the absence of overt movement during motor imagery. To date it is unclear how neural activations in motor imagery and execution compare for naturalistic whole-body movements, such as walking. Neuroimaging studies have not directly compared imagery and execution during dynamic walking movements.

Left Atrial Appendage Closure: Therapy Overview and Future Perspective.

The left atrial appendage (LAA) has gained increasing attention in the field of cardiology as a potential site for intervention in patients with atrial fibrillation (AF) and an elevated risk of thromboembolic events. Left atrial appendage occlusion (LAAO) has emerged as a promising therapeutic strategy to mitigate the risk of stroke and systemic embolism, especially in individuals who are unsuitable candidates for long-term anticoagulation therapy. This review aims to provide a comprehensive analysis of the current state of LAAO, encompassing its anatomic considerations, procedural techniques, clinical outcomes, and future directions.

A qualitative assessment of provider-perceived barriers to implementing family-based treatment for anorexia nervosa in low-income community settings.

Background: Family-based treatment (FBT) is a front-line empirically supported intervention for adolescent anorexia nervosa, but it is often inaccessible to families from lower income backgrounds, as it is most typically available in specialty research and private practice settings. In preparation for a pilot trial of FBT delivered in the home setting, this study qualitatively examined provider perceptions of implementing FBT in lower-income communities.

Methods: Eating disorder clinicians working in community clinics (therapists, medical doctors, dietitians, and social workers; n = 9) were interviewed about their experiences using FBT.

Experimental determination of the partitioning of representative organic pollutants to the air-water interface.

Using glancing-angle laser-induced fluorescence (GALIF) spectroscopy as a probe, the partitioning of naphthalene, fluoranthene, pyrene, umbelliferone, phenol red, and bisphenol A from bulk solution to the air-water interface was examined in both pure water and aqueous solutions of 6 mM octanol. Previous studies provided similar Langmuir adsorption isotherms for anthracene and imidazole 2-carboxaldehyde. The surface partitioning behaviour of each compound in both environments was well described using a Langmuir adsorption model; partitioning coefficients were derived from the fits to such isotherms.

The Use of Biofluid Markers to Evaluate the Consequences of Sport-Related Subconcussive Head Impact Exposure: A Scoping Review.

Background: Amidst growing concern about the safety of sport-related repetitive subconcussive head impacts (RSHI), biofluid markers may provide sensitive, informative, and practical assessment of the effects of RSHI exposure.

Objective: This scoping review aimed to systematically examine the extent, nature, and quality of available evidence from studies investigating the effects of RSHI on biofluid markers, to identify gaps and to formulate guidelines to inform future research.

Methods: PRISMA extension for Scoping Reviews guidelines were adhered to.

Photochemical renoxification on commercial indoor photoactive paint.

Surface chemistry plays an important role in the indoor environment owing to the large indoor surface to volume ratio. This study explores the photoreactivity of surfaces painted with a photoactive paint in the presence of NO. Two types of experiments are performed; illumination of painted surfaces with a nitrate deposit and illumination of painted surfaces in the presence of gaseous NO.

Revisiting the WFNS Score: Native Computed Tomography Imaging Improves Identification of Patients With "False Poor Grade" Aneurysmal Subarachnoid Hemorrhage.

Background And Objectives: In patients suffering from aneurysmal subarachnoid hemorrhage (aSAH), the optimal time to determine the World Federation of Neurosurgical Societies (WFNS) score remains controversial because of possible confounding factors. Goals of this study were (1) to analyze the most sensitive timepoint to determine the WFNS score in patients with aSAH and (2) to evaluate the impact of initial native computed tomography (CT) imaging on reducing the mismatch of "false poor grade" patients.

Methods: We retrospectively analyzed daily WFNS scores from admission until day 7 in 535 aSAH patients and evaluated their predictive value for the modified Rankin Scale at discharge and 6 months postbleeding.

Spontaneous Iodide Activation at the Air-Water Interface of Aqueous Droplets.

We present experimental evidence that atomic and molecular iodine, I and I, are produced spontaneously in the dark at the air-water interface of iodide-containing droplets without any added catalysts, oxidants, or irradiation. Specifically, we observe I formation within droplets, and I emission into the gas phase from NaI-containing droplets over a range of droplet sizes. The formation of both products is enhanced in the presence of electron scavengers, either in the gas phase or in solution, and it clearly follows a Langmuir-Hinshelwood mechanism, suggesting an interfacial process.

The evolving landscape of COVID-19 and post-COVID condition in patients with chronic lymphocytic leukemia: A study by ERIC, the European research initiative on CLL.

In this retrospective international multicenter study, we describe the clinical characteristics and outcomes of patients with chronic lymphocytic leukemia (CLL) and related disorders (small lymphocytic lymphoma and high-count monoclonal B lymphocytosis) infected by SARS-CoV-2, including the development of post-COVID condition. Data from 1540 patients with CLL infected by SARS-CoV-2 from January 2020 to May 2022 were included in the analysis and assigned to four phases based on cases disposition and SARS-CoV-2 variants emergence. Post-COVID condition was defined according to the WHO criteria.

Adapting family-based treatment for adolescent anorexia nervosa delivered in the home: A novel approach for improving access to care and generalizability of skill acquisition.

Background: Anorexia nervosa (AN) is a serious mental illness associated with high rates of morbidity and mortality. Family-based treatment (FBT) is a well-established treatment for adolescent AN, yet it is underutilized in community settings and is unavailable to many families, particularly those from lower income and racial and ethnic minority backgrounds. Furthermore, some families do not respond optimally to FBT, possibly because of challenges translating skills acquired in office-based treatment settings to naturalistic settings.