A clinical study to compare the anticalculus efficacy of three dentifrice formulations.

The objective of this double-blind clinical study, conducted in harmony with the accepted Volpe-Manhold design for studies of dental calculus, was to compare the supragingival anticalculus efficacy of three commercially available dentifrice formulations. The test toothpastes were Colgate Total Plus Whitening Toothpaste with an added high cleaning silica base, Crest Multi-Care Advanced Cleaning Toothpaste, and Colgate Winterfresh Gel. Adult male and female subjects from the northern New Jersey area were entered into the study based on a pre-test (baseline) Volpe-Manhold Calculus Index score of 7.

The clinical efficacy of Colgate Total Plus Whitening Toothpaste containing a special grade of silica and Colgate Total Fresh Stripe Toothpaste in the control of plaque and gingivitis: a six-month clinical study.

The objective of this six-month, placebo-controlled, double-blind clinical study, conducted in harmony with American Dental Association guidelines, was to provide an assessment of the effectiveness of a new dentifrice formulation of Colgate Total Toothpaste containing a special grade of silica (Colgate Total Plus Whitening Toothpaste), vs. Colgate Total Fresh Stripe Toothpaste as a control, and a placebo dentifrice without triclosan and the copolymer, for the control of supragingival dental plaque and gingivitis. Adult male and female subjects from the state of New Jersey were entered into the study, and stratified into three treatment groups which were balanced for baseline Quigley-Hein Plaque Index scores and baseline Löe-Silness Gingival Index scores.