Publications by authors named "Donald M Torre"
Article Synopsis
- The AJCC 8th edition guidelines recommend sentinel lymph node (SLN) biopsy for primary melanomas with at least 1 mm Breslow thickness, while the NCCN considers it for certain thinner lesions with specific adverse features.
- The introduction of the Sentinella gamma camera enhances SLN identification rates during surgery, improving accuracy over traditional methods.
- At the California Pacific Medical Center, a multidisciplinary approach involving various specialists collaborates to provide personalized and effective treatment for melanoma patients, and this model can be applied to other cancer types as well.*
Background: Technetium-99m-labeled Tilmanocept, a multivalent mannose, is readily internalized by the CD206 surface receptor on macrophages and dendritic cells which are abundantly present in lymph nodes. We want to examine the drainage patterns of Technetium-99m-labeled Tilmanocept to sentinel lymph nodes (SLNs) in melanoma patients following the 10% rule.
Methods: Multi-center retrospective review of patients with cutaneous melanoma undergoing SLN biopsy using Technetium-99m-labeled Tilmanocept between 2008 and 2014 was conducted.
The article "Intraoperative Imaging with a Portable Gamma Camera May Reduce the False-Negative Rate for Melanoma Sentinel Lymph Node Surgery," written by Stanley P. Leong et al., was originally published electronically on the publisher's internet portal (currently SpringerLink) on August 13, 2018, without open access.
View Article and Find Full Text PDFBackground: Preoperative imaging and intraoperative gamma probe (GP) localization is standard for identifying sentinel lymph nodes (SLNs) in melanoma patients. The aim of this prospective Institutional Review Board-approved study was to investigate whether an intraoperative portable gamma camera (PGC) improves SLN detection over the GP.
Methods: Lymphoscintigraphy and single photon emission computed tomography/computed tomography were performed after injection of 99mTc-Tilmanocept in melanoma patients (≥ 18 years, Breslow thickness ≥ 1.