Publications by authors named "Donald James Gomes"

Article Synopsis
  • The rising antimicrobial resistance in Providencia stuartii, especially in immunocompromised and burn patients in Bangladesh, necessitates urgent investigation, as this pathogen was previously underrecognized.
  • Two strains isolated from critically injured burn patients displayed multidrug resistance, with one strain resistant to all 22 tested antibiotics and showing concerning genetic features linked to carbapenem resistance.
  • A comprehensive genome-wide analysis revealed significant genetic diversity and resistance gene prevalence within P. stuartii, raising public health concerns about its adaptability and potential for cross-species transmission.
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Article Synopsis
  • The study focuses on the extensively drug-resistant strain of Pseudomonas aeruginosa isolated from a burn wound, highlighting its role in severe infections.
  • Whole genome sequencing was performed to analyze the strain's genomic features, including its resistance to 14 antibiotics and various virulence factors.
  • The research identifies this strain as the first extensively drug-resistant ST 357 P. aeruginosa reported from Bangladesh, indicating a need for further investigation into high-risk clones in the region.*
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In clinical cholera, a 3-day course of antibiotic complements extensive rehydration therapy by reducing stool volume, shortening the illness, and averting death. However, antibiotic therapy, which has lifesaving implications for cholera, is often hindered due to multidrug resistance in Vibrio cholerae, the cause of cholera. Crude aqueous mixture and water soluble methanol extract from leaf and bark of Psidium guajava, a tropical fruit guava of the family Myrtaceae, showed strong antibacterial activity against multidrug-resistant V.

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Pathogenic Escherichia coli remains important etiological agent of infantile diarrhea in Bangladesh. Previous studies have focused mostly on clinical strains, but very little is known about their presence in aquatic environments. The present study was designed to characterize potentially pathogenic E.

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One hundred and fifty-one patients, clinically suspected for pulmonary tuberculosis (age: 31 +/- 13 years, male/female: 112/39), were investigated to evaluate the diagnostic potential of polymerase chain reaction (PCR) based detection of the Mycobacterium tuberculosis complex in sputum. The diagnostic efficacy of PCR was compared with culture of Mycobacterium tuberculosis on egg-based Lowenstein-Jensen modified medium. PCR detected 71.

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