Iron overload in adults with sickle cell disease who have received intermittent red blood cell transfusions.

Objective: To assess the prevalence of iron overload in adults with sickle cell disease (SCD) not on a chronic transfusion protocol.

Design: Retrospective chart review.

Data Source: University of South Alabama Comprehensive Sickle Cell Center adult outpatient clinic.

Misclassification of pulmonary hypertension in adults with sickle hemoglobinopathies using Doppler echocardiography.

Objective: To compare the diagnostic utility of Doppler echocardiography-derived tricuspid regurgitant jet velocity (TRV) ≥ 2.5 m/s to right heart catheterization (RHC) in defining pulmonary hypertension (PH) in adult patients with sickle cell disease (SCD).

Methods: This is a retrospective chart review of adults with SCD who had a TRV ≥ 2.