Transposon-mediated transgenesis in the frog: New tools for biomedical and developmental studies.

The amphibian, Xenopus laevis has been an excellent developmental model for over half a century. The large egg size, external fertilization and simple husbandry make this frog an ideal tool to study early vertebrate development. The tetraploid genome and long generation time, however, has hindered the use of X.