Publications by authors named "Donal J O'Brien"
Prenatal detection of placenta accreta spectrum using a sonographic checklist.
Acta Obstet Gynecol Scand
October 2024
Article Synopsis
- The study evaluates a proposed ultrasound checklist for detecting placenta accreta spectrum (PAS) in patients with a high likelihood of the condition, aiming to see how effective it is in identifying confirmed PAS cases.
- Conducted over five years, the research included patients who had ultrasound assessments for PAS suspicion, with diagnoses confirmed through surgical and histopathological findings.
- Results showed an 80.7% PAS diagnosis among participants, with the third-trimester ultrasound displaying a sensitivity of 84% and specificity of 73%, highlighting key ultrasound features—abnormal placental lacunae and myometrial thinning—as strongly associated with PAS.
Objective: to evaluate fetal growth in pregnancies complicated by placenta accreta spectrum (PAS) and to compare fetal growth between cases stratified by ultrasound stage of PAS.
Methods: This was a prospective multicenter cohort study of women diagnosed with PAS between January 2018 and December 2021. We grouped participants into cases by ultrasound stage (PAS stage 1-3) and controls (PAS0).
Aim: The purpose of this study is to compare maternal outcomes in patients with placenta accreta spectrum (PAS) when managed as part of a multi-disciplinary team (MDT) compared to standard care.
Methods: Patients in the standard care group were retrospectively identified from pathology records, with patients in the MDT group prospectively collected on an electronic database. Data on maternal demographics, delivery, estimated blood loss (EBL), transfusion requirements, and morbidity were recorded.