Global Incidence, Risk Factors, and Temporal Trends of Adrenal Cancer: a systematic analysis of cancer registries.

Objectives: Adrenal gland cancer (AGC) is a rare cancer with a poor prognosis. Studies on this cancer have been limited. This study, for the first time, aims to analyse the global disease burden and trends of adrenal gland cancer in country level and examine lifestyle and socioeconomic risk factors to generate hypotheses.

Leveraging AI to optimize vaccines supply chain and logistics in Africa: opportunities and challenges.

Examining the current situation of the vaccine supply chain in Africa, the article highlights the importance of AI technologies while outlining the prospects and problems in vaccine supply chain management in Africa. Despite the significance of vaccinations, many African children are unable to receive them due to logistical challenges and a lack of infrastructure. AI has the potential to increase productivity by streamlining logistics and inventory management, but it is hampered by issues with data privacy and technology infrastructure.

Distribution, Risk Factors and Epidemiological Trends of Pancreatic Cancer Across Countries' Income Levels: A Comprehensive Analysis.

Background: Globally, pancreatic cancer poses a significant concern for public health.

Aims: The objective of this study was to assess the burden of pancreatic cancer on varying income levels.

Methods And Results: Data from the Global Burden of Disease Study (GBD) 2021 and Gross Domestic Product Per Capita data were utilised in this study.

Climate change trauma and collective dissociation: Unraveling the impact on mental health and advocating for collective action.

The climate change crisis is a complex global challenge that has far- reaching implications for public health and well-being. Rising temperatures and more frequent extreme weather events are impacting physical health, mental well-being, and ecological balance. Vulnerable communities are disproportionately affected, especially in terms of food security.

The Effects of Sudan's Armed Conflict on Economy and Health: A Perspective.

Sudan's economy has been greatly affected by the armed conflict through 15 different channels at both micro and macro levels. The requested fund to save live of sudanese population is 2.6 billion US$ from which only 33% was allocated.

Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries.

Cancer is a major global health challenge, with approximately 19.3 million new cases and 10 million deaths estimated by 2020. Laboratory advancements in cancer detection have transformed diagnostic capabilities, particularly through the use of biomarkers that play crucial roles in risk assessment, therapy selection, and disease monitoring.

Self-rated health differences between exclusive e-cigarette users and exclusive cigarette smokers: evidence from the 2017-2019 Scottish Health Survey.

The comparative health implications of e-cigarette use versus traditional cigarette smoking remain a critical focus in public health research. This cross-sectional study examined differences in self-rated general health between exclusive e-cigarette users and exclusive cigarette smokers, using data from the 2017-2019 Scottish Health Survey. A total of 2484 adults (aged 16 and above) were included and categorized as exclusive e-cigarette users (n = 565) or exclusive cigarette smokers (n = 1919).

Antimicrobial Resistance on Ships: A Narrative Review.

Antimicrobial resistance (AMR) poses a global health challenge, particularly in maritime environments where unique conditions foster its emergence and spread. Characterized by confined spaces, high population density, and extensive global mobility, ships create a setting ripe for the development and dissemination of resistant pathogens. This review aims to analyse the contributing factors, epidemiological challenges, mitigation strategies specific to AMR on ships and to propose future research directions, bridging a significant gap in the literature.

Challenges and opportunities of artificial intelligence in African health space.

The application of artificial intelligence (AI) to healthcare in Africa has the potential to transform productivity, diagnosis, disease surveillance, and resource allocation by improving accuracy and efficiency. However, to fully realize its benefits, it is necessary to consider issues concerning data privacy, equity, infrastructure integration, and ethical policy development. The use of these tools may improve the detection of diseases, the distribution of resources, and the continuity of care.

Vesicular Stomatitis Virus: Insights into Pathogenesis, Immune Evasion, and Technological Innovations in Oncolytic and Vaccine Development.

Vesicular stomatitis virus (VSV) represents a significant advancement in therapeutic medicine, offering unique molecular and cellular characteristics that make it exceptionally suitable for medical applications. The bullet-shaped morphology, RNA genome organization, and cytoplasmic replication strategy provide fundamental advantages for both vaccine development and oncolytic applications. VSV's interaction with host cells through the low-density lipoprotein receptor (LDL-R) and its sophisticated transcriptional regulation mechanisms enables precise control over therapeutic applications.

Addressing the emerging threat of Oropouche virus: implications and public health responses for healthcare systems.

Oropouche fever is an increasingly significant health concern in tropical and subtropical areas of South and Central America, and is primarily spread by midge vectors. The Oropouche virus (OROV) was first identified in 1955 and has been responsible for numerous outbreaks, particularly in urban environments. Despite its prevalence, the disease is often under-reported, making it difficult to fully understand its impact.

Achieving malaria-free: Egypt's journey to WHO certification and global implications for disease control.

Egypt's recent malaria-free certification by the World Health Organization (WHO) marks a significant achievement in public health, underscoring the effectiveness of sustained national efforts in disease eradication. This milestone, achieved after nearly a century of strategic intervention, highlights the importance of integrated public health programmes and cross-sector collaboration. Egypt's journey involved early initiatives to reduce human-mosquito contact, the establishment of malaria control stations, and comprehensive outbreak management strategies.

Incidence, risk factors, and epidemiological trends of tracheal cancer: a global analysis.

Background: Tracheal cancer is a rare malignancy with limited research but high mortality rates. This study aims to analyse recent data to understand the global burden, trends, and risk factors for tracheal cancer, facilitating improved prevention and treatment strategies.

Methods: We conducted a study on tracheal cancer using data from the Global Cancer Observatory and the Cancer Incidence in Five Continents databases.

CRISPR-Cas Systems in the Fight Against Antimicrobial Resistance: Current Status, Potentials, and Future Directions.

Background: Antimicrobial resistance (AMR) is a critical global health concern that threatens the efficacy of existing antibiotics and poses significant challenges to public health and the economy worldwide. This review explores the potential of CRISPR-Cas systems as a novel approach to combating AMR and examines current applications, limitations, and prospects.

Methods: A comprehensive literature search was conducted across multiple databases, including PubMed, Google Scholar, Scopus, and Web of Science, covering publications published from 2014 to August 2024.

Challenges, Health Risks and Recommendations on Meat Handling Practices in Africa: A Comprehensive Review.

Meat handling is a crucial aspect of public health as it forms complex interactions among humans, animals, and the environment. African meat handlers continue to face various challenges in slaughterhouses that significantly impact their lives and the general public during meat processing. This paper reviews the challenges meat handlers encounter and the associated risks of improper meat handling in various African slaughterhouses.

Comparison of the quality of life of comorbid and non-comorbid people living with HIV/AIDS in a Nigerian secondary healthcare facility.

Introduction: Quality of life (QoL) is a vital healthcare indicator among people living with human immunodeficiency virus (PLWHA). Assessing the effects of comorbidities on QoL among PLWHA is of clinical and public health importance. This study compared the QoL of comorbid and non-comorbid PLWHA at St.

The African Medicines Agency and Medicines Regulation: Progress, challenges, and recommendations.

In response to the situation of the African healthcare system, the African Medicines Agency (AMA) was established by the African Union (AU) to regulate access to medicines and support the local manufacture of medications. This study aimed to describe the factors that enabled the establishment of the African Medicines Agency and its successes, challenges, and perceived benefits. We reviewed data sources that explored the progress and challenges of the African Medicines Agency and Medicines Regulation in Africa.

The Evolving Role of Palliative Care in Older People with Glioblastoma.

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in older adults and has a poor prognosis and limited response to treatment. The growing impact of palliative care on older people undergoing neurosurgery is becoming increasingly important. Palliative care aims to improve the quality of life for people and their families by addressing their physical, psychosocial, and spiritual needs.

Restrictive migration policies and their impact on HIV prevention, care and treatment services.

Migration policies have a significant impact on population health, particularly for individuals living with human immunodeficiency virus (HIV). These policies not only determine who is allowed to enter a country but also influence which immigrants can access services provided by the government. Some countries continue to impose restrictions on HIV-positive individuals, justifying these measures as necessary to protect public health and mitigate healthcare and economic concerns.

Incidence distributions, risk factors and trends of vaginal cancer: A global population-based study.

Objective: This study aimed to investigate the incidence, risk factors and trends for vaginal cancer.

Design: Retrospective observational design.

Setting: Data were collected from multiple sources, including the Global Cancer Observatory, Cancer Incidence in Five Continents Plus, Global Burden of Disease, World Bank and the United Nations.

Looking Beyond the Lens of Crimean-Congo Hemorrhagic Fever in Africa.

Crimean-Congo hemorrhagic fever (CCHF) is a lethal viral disease that has severe public health effects throughout Africa and a case fatality rate of 10%-40%. CCHF virus was first discovered in Crimea in 1944 and has since caused a substantial disease burden in Africa. The shortage of diagnostic tools, ineffective tick control efforts, slow adoption of preventive measures, and cultural hurdles to public education are among the problems associated with continued CCHF virus transmission.

Global burden, risk factors, and temporal trends of ureteral cancer: a comprehensive analysis of cancer registries.

Background: Ureteral cancer is a rare cancer. This study aimed to provide an up-to-date and comprehensive analysis on the global trends of ureteral cancer incidence and its association with lifestyle and metabolic risk factors.

Methods: The incidence of ureteral cancer was estimated from the Cancer Incidence in Five Continents Plus and Global Cancer Observatory databases.