C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases.

Deposits of the terminal-membrane-attack-complex (MAC) C5b-9 on perfascicular endomysial capillaries are generally regarded as diagnostic hallmark of dermatomyositis (DM). Although the pathophysiology is not clear, C5b-9 deposits on capillaries seem to be associated with microinfarctions and vascular damage. Here, we report on a series of 19 patients presenting with C5b-9 accumulation on endomysial capillaries in the absence of features for DM.

Rare mimicry of meningioma: angioleiomyoma of the falx.

Background: Angioleiomyomas (ALMs) are benign soft tissue tumors composed of various size vessels with abundant intervening smooth muscles. Intracranial ALMs are exceedingly rare with 12 reported cases to date presenting as extracerebral masses that mimic cerebral cavernous malformation or meningiomas.

Objective: We report a case of intracranial ALM of the falx cerebri imitating an atypical meningioma or hemangiopericytoma.

Experimental subacute spinal cord compression: correlation of serial S100B and NSE serum measurements, histopathological changes, and outcome.

Objective: To correlate serial measurements of serum S100B and neuron-specific enolase (NSE) with histopathological changes of the spinal cord and to assess their prognostic significance in a set-up of experimental spinal cord compression.

Methods: The thoracic cords of 22 rabbits were increasingly compressed and decompressed once paresis had developed. After decompression, outcome was rated as favorable or unfavorable.