A Role for History in Inclusive Nursing Education.

Background: History is a critical methodology that provides perspective on complex issues in health care today.

Method: This article draws on a selection of interdisciplinary scholarship on the history of nursing and health care, including work by scholars of color; lesbian, gay, bisexual, transgender, queer or questioning (LGBTQ+) scholars; and disability studies scholars, to demonstrate the role of history in inclusive nursing education.

Results: History provides critical perspective regarding how race, gender, class, sexuality, and disability have shaped the development of nursing and the health care system, affected who has been able to access education and careers in nursing, and influenced Americans' access to and experiences of health care.

Nursing's Boundary Work: Theory Development and the Making of Nursing Science, ca. 1950-1980.

Background: Beginning in the late 1950s and intensifying through the 1960s and 1970s, nurse educators, researchers, and scholars worked to establish nursing as an academic discipline. These nursing leaders argued that the development of nursing theory was not only critical to nursing's academic project but also to improving nursing practice and patient care.

Objectives: The purpose of the article is to examine the context for the development of nursing theory and the characteristics of early theory development from the 1950s through the early 1980s.

Plow, town, and gown: the politics of family practice in 1960s America.

In the 1960s, general practitioners organized themselves into a state-based nationwide political movement that lobbied state legislators and state-funded medical schools to create departments of family practice. They framed their calls in the context of the national shortages of primary care physicians by arguing that those medical schools that received state funding had an obligation to the state to train sufficient numbers of primary care physicians to ensure the health care needs of the state's residents would be met. As this article reveals, two defining features of this activism were rural politics and the politics of town and gown.

"Coming to grips with the nursing question": the politics of nursing education reform in 1960s America.

The 1950s and 1960s were decades of change for the American nursing profession. A new generation of nurse educators sought to create greater professional autonomy for the nurse by introducing new models of education that emphasized science-based learning over technical skills and bedside care, and creating new clinical roles for the nurse, based on advanced graduate education. They confronted resistance from an older generation of nurses who feared becoming "second-class citizens" in increasingly academic nursing schools, and from academic health care institutions all too comfortable with the gendered hierarchy on which the traditional model of nursing education and practice was predicated.

Bioequivalence: the regulatory career of a pharmaceutical concept.

Generic drugs cannot be marketed without regulatory and clinical demonstration of "bioequivalence." The authors argue that the concept of "bioequivalence" is a joint regulatory and scientific creation, not purely a technical concept, and not purely a legal concept. It developed at the interstices of networks of pharmacologists, regulators, food and drug lawyers, and American and European policy makers interested in "generic" drugs.

"Who's winning the human race?"Cold war as pharmaceutical political strategy.

Between 1959 and 1962, Senator Estes Kefauver led a congressional investigation into the pricing practices of U.S. drug firms.

Allied against reform: pharmaceutical industry-academic physician relations in the United States, 1945-1970.

During the 1960s, the drug industry was the subject of two congressional investigations into its business practices and pricing policies, and in 1962, passage of the Drug Amendments mandated greater Food and Drug Administration authority over pharmaceutical development. In this article, I examine the industry's efforts to circumvent these political challenges by drawing on its longstanding relationship with academic physicians and the American Medical Association. Using the medical profession's shared concern about expanding government oversight over therapeutic practice, the industry called on academic physicians to join forces with it and establish an expert advisory body to guide government officials on pharmaceutical policy.

Identification of in vitro folding conditions for procathepsin S and cathepsin S using fractional factorial screens.

Human procathepsin S and cathepsin S were expressed as inclusion bodies in Escherichia coli. Following solubilization of the inclusion body proteins, fractional factorial protein folding screens were used to identify folding conditions for procathepsin S and cathepsin S. A primary folding screen, including eight factors each at two levels, identified pH and arginine as the main factors affecting procathepsin S folding.