Objectives: Techniques for quantitative pulmonary perfusion and ventilation using the Fourier Decomposition method were recently demonstrated. We combine these two techniques and show that ventilation-perfusion (V/Q) imaging is possible using only a single MR acquisition of less than thirty seconds.
Methods: The Fourier Decomposition method is used in combination with two quantification techniques, which extract baselines from within the images themselves and thus allows quantification.
Objective: The Fourier decomposition (FD) method is a noninvasive method for assessing ventilation and perfusion-related information in the lungs, but the lack of quantifiable values is a drawback. We demonstrate a novel technique for quantification of the FD ventilation maps, compare it to two published methods, and show results from both healthy volunteers and patients diagnosed with lung cancer.
Materials And Methods: We quantified the standard FD ventilation images by utilizing additional information, i.
Purpose: To quantitatively evaluate lung perfusion using Fourier decomposition perfusion MRI. The Fourier decomposition (FD) method is a noninvasive method for assessing ventilation- and perfusion-related information in the lungs, where the perfusion maps in particular have shown promise for clinical use. However, the perfusion maps are nonquantitative and dimensionless, making follow-ups and direct comparisons between patients difficult.
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