Publications by authors named "Dominique Luyts"
Respiratory Syncytial Virus Disease Burden in Community-Dwelling and Long-Term Care Facility Older Adults in Europe and the United States: A Prospective Study.
Open Forum Infect Dis
April 2023
Background: Data on respiratory syncytial virus (RSV) disease burden in adults remain scarce. We assessed the burden of confirmed RSV-acute respiratory infections (cRSV-ARIs) in community-dwelling (CD) adults and those in long-term care facilities (LTCFs).
Methods: In this prospective cohort study covering 2 RSV seasons (October 2019-March 2020 and October 2020-June 2021), RSV-ARIs were identified through active surveillance, in medically stable CD-adults ≥50 years (Europe) or adults ≥65 years in LTCFs (Europe and the United States).
Article Synopsis
- This study investigates how common respiratory syncytial virus (RSV)-positive acute respiratory infections (ARI) were among older adults in southeast Minnesota before and during the COVID-19 pandemic, analyzing data from 2,325 participants over two RSV seasons (2019-2021).
- Researchers found that before the pandemic, the incidence rate of RSV-positive ARI was 48.6 cases per 1,000 person-years, but during the pandemic, no cases were reported, indicating a significant drop in RSV infections during that time.
- Additionally, the study measured the quality of life and physical function of participants after recovering from RSV-positive ARI, demonstrating the long-term impact of RSV infections on
Reduced antigen diphtheria-tetanus-acellular pertussis (Tdap) vaccination is included in the maternal immunization program in Brazil since September 2014. We investigated associations between maternal Tdap vaccination and pregnancy-related adverse events (AEs) (gestational diabetes, pregnancy-related hypertension, and pregnancy hemorrhage) and neonatal AEs of interest (preterm birth and small for gestational age). This descriptive, observational, retrospective, single-center study in Brazil (NCT02757950) compared data from medical charts of 1203 pregnant women who received Tdap as part of the maternal immunization program and delivered between May 2015 and February 2017 (exposed cohort) and 1259 unvaccinated women who delivered between September 2012 and August 2014 (unexposed cohort).
View Article and Find Full Text PDFObjective: To generate country-specific data on age of sexual debut in young adults in 7 European countries with regard to the optimal age for prophylactic human papillomavirus (HPV) vaccination.
Methods: Survey of self-reported sexual debut and behavior in a sample of young adults aged 18-24 years in 7 European countries (Czech Republic, Ireland, Italy, Netherlands, Poland, Russia, France). Subjects (minimum of 500 males and 500 females per country) were recruited at public places using an in-street collecting approach in all countries except France, where the survey was conducted at home.