Publications by authors named "Dominique Lisa Birrer"

Article Synopsis
  • Metabolic-bariatric surgery (MBS) is the best treatment for obesity, but many patients experience recurrent weight gain after Roux-en-Y gastric bypass (RYGB), leading to associated health issues; gastric pouch resizing (GPR) offers a low-risk solution for this weight regain.
  • A study involving 48 patients who underwent GPR after RYGB showed significant weight stabilization over time, with a mean follow-up indicating an improvement in BMI and resolution of obesity-related health conditions in more than half of the participants.
  • The procedure was determined to be safe, with low rates of complications, and patients reported high satisfaction levels, making GPR a worthwhile option for those struggling with weight regain post-surgery.
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Postoperative complications represent a major public health burden worldwide. Without standardized, clinically relevant and universally applied endpoints, the evaluation of surgical interventions remains ill-defined and inconsistent, opening the door for biased interpretations and hampering patient-centered health care delivery. We conducted a Jury-based consensus conference incorporating the perspectives of different stakeholders, who based their recommendations on the work of nine panels of experts.

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Article Synopsis
  • Surgical liver failure (SLF) can occur after surgeries where too much liver tissue is removed, often leading to high mortality rates, but its causes are not well understood.
  • Researchers used mouse models of different liver surgeries to investigate the effects of blood flow and oxygen levels on SLF, finding that early hypoxia contributes to the problem.
  • They discovered that boosting lipid oxidation through treatments like L-carnitine can improve liver regeneration and survival rates in both mice and patients, suggesting that enhancing lipid oxidation could be a promising strategy to mitigate SLF risks in clinical settings.
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Robotic proctectomy has been shown to lead to better functional outcomes compared to laparoscopic surgery in rectal cancer. However, in ulcerative colitis (UC), the potential value of robotic proctectomy has not yet been investigated, and in this indication, the operation needs to be adjusted to the total colectomy typically performed in the preceding 6 months. In this study, we describe the technique and analyze outcomes of a staged laparoscopic and robotic three-stage restorative proctocolectomy and compare the clinical outcome with the classical laparoscopic procedure.

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Background: Centralisation of highly specialised medicine (HSM) has changed practice and outcome in pancreatic surgery (PS) also in Switzerland. Fewer hospitals are allowed to perform pancreatic surgery according to nationally defined cut-offs.

Objective: We aimed to examine trends in PS in Switzerland.

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Background: The aim of this study was to evaluate if the time of day a cholecystectomy was performed affects in-hospital complication rates and mortality.

Methods: A national quality measurement database was retrospectively studied. Study period was 2010 to 2017.

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Objective: In a surgical career, teaching of surgical procedures plays a central role. In this study we want to evaluate the influence of teaching in appendectomies on the in-hospital outcome.

Design And Setting: Retrospectively, 26,436 cases from the national quality measurement database (AQC) between the years 2009 and 2017 were evaluated using the diagnosis and the procedure codes.

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Introduction: Acute appendicitis is among the most common indications for emergency abdominal surgery. The risk of perforation might increase with a delay in treatment. Therefore, appendicitis is considered a surgical emergency, leading to appendectomies being frequently performed off-hours.

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Engineered muscle constructs provide a promising perspective on the regeneration or substitution of irreversibly damaged skeletal muscle. However, the highly ordered structure of native muscle tissue necessitates special consideration during scaffold development. Multiple approaches to the design of anisotropically structured substrates with grooved micropatterns or parallel-aligned fibres have previously been undertaken.

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