Publications by authors named "Dominique Fasel"
Article Synopsis
- * Daphnia magna, a small freshwater crustacean, exhibits a unique case where a dominant female sex-determining locus exists alongside its typical ESD, mapping to a low-recombining region in its genome.
- * The identified genomic region, which functions similarly to a sex-related supergene and contains key genes for sex differentiation, may offer insights into the evolutionary processes behind the development of sex chromosomes.
We investigated the pharmacokinetics of intraperitoneal administration of daptomcyin in a peritoneal dialysis (PD) patient treated for a pacemaker infection with Staphylococcus epidermidis. After initial start of intravenous daptomycin at 9 mg/kg body weight every 48 hours, the therapy was switched to intraperitoneal administration of 5.3 mg/kg body weight in 1 L icodextrin 7.
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- Many organisms have cryptic breeding systems that influence their ecology and evolution, making them hard to study through traditional observational methods.
- Genomic approaches, such as analyzing genetic transmission from parents to offspring, can help understand these systems, especially in cases like Daphnia magna where self-fertilization and automictic parthenogenesis are compared.
- This study confirms that offspring produced by automixis, primarily through terminal fusion, can be distinguished from those produced by self-fertilization using genome-wide heterozygosity data, highlighting the value of genomic techniques in revealing breeding mechanisms.
Aims: HIV infection may be associated with an increased recurrence rate of myocardial infarction. Our aim was to determine whether HIV infection is a risk factor for worse outcomes in patients with coronaray artery disease.
Methods: We compared data aggregated from two ongoing cohorts: (i) the Acute Myocardial Infarction in Switzerland (AMIS) registry, which includes patients with acute myocardial infarction (AMI), and (ii) the Swiss HIV Cohort Study (SHCS), a prospective registry of HIV-positive (HIV+) patients.
We report on a 65-year-old male patient with a Shiga toxin-producing Escherichia coli O51:H49 gastrointestinal infection and sepsis associated with hemolytic uremic syndrome (HUS) with a fatal outcome. The strains isolated harbored stx2e and eae, a very unusual and new virulence profile for an HUS-associated enterohemorrhagic E. coli.
View Article and Find Full Text PDFBackground: We aimed to evaluate the accuracy and acceptability of a short screening test battery for mild neurocognitive deficits.
Methods: HIV-infected individuals with a suppressed viral load were examined at the University Hospital Basel with a screening test consisting of a questionnaire and selected cognitive tests, administered by trained nurses, followed by an in-depth neuropsychological examination. Test acceptance was evaluated with a questionnaire.
Premise Of The Study: Because seeds have essential functions in the life cycle of plants, even subtle changes in their characteristics may have important demographic consequences. In this study, we examined whether potential changes in seed characteristics as a result of polyploidy or postintroduction evolution may have contributed to the invasion of Centaurea stoebe (Asteraceae). This plant occurs as diploid and tetraploid cytotypes in its native range in Europe, whereas only tetraploids have been found and become invasive in North America.
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