Publications by authors named "Dominique Baratin"

Introduction: Increased human immunodeficiency virus (HIV) virulence at infection has been suggested by a meta-analysis based on viral load and CD4 T lymphocytes (CD4) count during acute infection. This result was obtained after secondary analyses of large databases, facilitating the detection of differences. Similar finding in cohorts of more modest sample size would indicate that the effect could be more substantial.

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Background: Compliance with official recommendations can be assessed by evaluating vaccination coverage (VC) in populations. The main objective of our study was to assess VC of adults against diphtheria, tetanus, poliomyelitis and pertussis (dTPaP) according to age. The second objective was to explore if vaccination status could be confirmed by documentation.

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Article Synopsis
  • - The study examined risk factors related to HIV-infected patients in Lyon, France, who presented for care with a CD4 cell count of ≤ 200 cells/mm³ between 1992 and 2006, highlighting significant demographics and characteristics.
  • - Among 3,569 patients analyzed, 31.9% had a CD4 count ≤ 200 cells/mm³, with older age, male gender, certain routes of transmission, migrant status, and regional differences identified as key risk factors for this lower count at first presentation.
  • - The research found a stark contrast in mortality rates, with 24.4% of patients in the lower CD4 group dying compared to only 4.1% in the higher group
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Purpose: To describe trends of urinary catheter-related infections (UCRIs) acquired by patients hospitalized in intensive care units (ICU) in relation with an infection control program.

Materials And Methods: Prospective surveillance in one ICU of a university hospital in Lyon (France) between 1995 and 2004.

Results: A 66% reduction of urinary catheter-related infections (UCRIs) acquired by patients hospitalized was observed between 1995 and 2004 after adjustment on age, gender, antibiotic use at admission, and duration of exposure to urinary catheter.

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The rate of HIV disease progression is associated with the severity of the acute retroviral syndrome (ARS). We explored the clinical features of ARS by gender, age and route of infection among 378 individuals with documented ARS enrolled in 5 prospective cohort studies with similar enrollment criteria. No major differences were detected by gender or by age.

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