Publications by authors named "Dominique B Hoelzinger"
Page 1 of 1
Synopsis of recent research by authors named "Dominique B Hoelzinger"
- Recent research by Dominique B Hoelzinger focuses on the interplay between immune responses and tumor biology, particularly how extracellular factors influence conditions like multiple myeloma and other cancers.
- A significant discovery was made with the identification of hepatoma-derived growth factor (HDGF) as a key protein present in extracellular vesicles from multiple myeloma cells, impacting tumor progression and cell proliferation upon knockdown.
- Additionally, Hoelzinger has explored the roles of non-coding RNAs during B cell differentiation, the effects of IL9 on T cell responses in cancer, and the immunosuppressive properties of regulatory T and macrophage cells in tumor microenvironments, highlighting potential therapeutic targets for improving antitumor immunity.
