Publications by authors named "Dominika Wysocka"
Introduction: Due to the widespread occurrence of acrylamide in the environment, its likely carcinogen status, and the suitability of the pig model as a human analogue, the authors decided to evaluate the impact of high and low doses of this compound on the processes of erythropoiesis in swine bone marrow.
Material And Methods: The experiment was carried out on Danish Landrace pigs at the age of eight weeks and body weight about 20 kg. The animals were divided into three equal groups consisting of five pigs in each.
Introduction: Statins are pharmacological agents commonly used to lower serum cholesterol level. The aim of the experiment was to investigate the effect of the statin simvastatin on thrombopoiesis in the porcine model because it is the closest to the human one regarding physiological and genetic similarities.
Material And Methods: The study was conducted on a group of 32 pigs randomly divided into two equal groups: control and experimental.
Global gene expression in liver transcriptome varies among cattle breeds. The present investigation was aimed to identify the differentially expressed genes (DEGs), metabolic gene networks and metabolic pathways in bovine liver transcriptome of young bulls. In this study, we comparatively analyzed the bovine liver transcriptome of dairy (Polish Holstein Friesian (HF); = 6), beef (Hereford; = 6), and dual purpose (Polish-Red; = 6) cattle breeds.
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- - Bisphenol A (BPA) is a common industrial chemical found in various products like packaging, CDs, and contact lenses, but its effects on human health, particularly on bone marrow cells, are not fully understood.
- - An experiment evaluated the impact of two BPA doses (0.05 mg/kg and 0.5 mg/kg) on erythroblastic cell lines in porcine bone marrow, assessing the number of cells before and after BPA exposure.
- - Results showed decreased production of erythroblastic cells and signs of anemia in both dosage groups, indicating that both high and low doses of BPA negatively affect blood cell production.
Introduction: Simvastatin is a substance which is commonly used as a medicine to reduce cholesterol level. Unfortunately, it shows numerous side effects. Simvastatin affects various internal organs, and among other detriments to health may cause persistent muscle weakness, osteolytic processes, headaches, and rashes.
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