Publications by authors named "Dominik Sikorski"

In the interests of using green and sustainable chemical innovations to create sustainable products with minimized (or no) chemical hazard potential, the polyester fabric in this work was activated and functionalized with chitosan and its durability was investigated. Chitosan is a natural biopolymer derived from chitin. As it has good biocompatibility, bio-absorption, anti-infectious, antibacterial and hemostatic properties and accelerates wound healing, it is increasingly being researched for the antimicrobial treatment of textiles.

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This work presents the results of research on obtaining chitosan (CS) films containing on their surface ciprofloxacin (CIP). A unique structure was obtained that not only gives new properties to the films, but also changes the way of coverage and structure of the surface. The spectroscopic test showed that in the process of application of CIP on the surface of CS film, CIP was converted from its crystalline form to an amorphic one, hence improving its bioavailability.

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New scaffold materials composed of biodegradable components are of great interest in regenerative medicine. These materials should be: stable, nontoxic, and biodegrade slowly and steadily, allowing the stable release of biodegradable and biologically active substances. We analyzed peptide-polysaccharide conjugates derived from peptides containing RGD motif (H-RGDS-OH (), H-GRGDS-NH (), and cyclo(RGDfC) ()) and polysaccharides as scaffolds to select the most appropriate biomaterials for application in regenerative medicine.

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Chitosan acquires bacteriostatic properties via protonation of its amino groups. However, much of the literature assumes that chitosan itself inhibits the growth of bacteria. This article presents a comparative study of chitosan nonwovens modified with various acids, including acetic, propionic, butyric, and valeric organic acids, as well as hydrochloric acid.

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This paper presents a comparative study on chitosan degradation in organic acid solutions according to their different dissociation characteristics. More precisely, the aim of the study was to determine the kinetics of the degradation process depending on the different acid dissociation constants (pKa values). The scientists involved in chitosan to date have focused mainly on acetic acid solutions.

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