Publications by authors named "Dominik Jenca"
Background: Growth differentiation factor (GDF)-15 is a pleiotropic cytokine that is associated with appetite-suppressing effects and weight loss in patients with malignancy.
Objectives: This study aims to investigate the relationships between GDF-15 levels, anorexia, cachexia, and clinical outcomes in patients with advanced heart failure with reduced ejection fraction (HFrEF).
Methods: In this observational, retrospective analysis, a total of 344 patients with advanced HFrEF (age 58 ± 10 years, 85% male, 67% NYHA functional class III), underwent clinical and echocardiographic examination, body composition evaluation by skinfolds and dual-energy x-ray absorptiometry, circulating metabolite assessment, Minnesota Living with Heart Failure Questionnaire, and right heart catheterization.
Background: Data on the clinical significance of iron deficiency (ID) in patients with myocardial infarction (MI) are conflicting. This may be related to the use of various ID criteria. We aimed to compare the association of different ID criteria with all-cause mortality after MI.
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- A study aimed to create a new score, called the PragueMi score, to predict mortality risk in patients after a myocardial infarction (heart attack) by using heart failure (HF) symptoms along with clinical factors.
- The study analyzed data from 1,135 patients and found that key variables like age, history of heart failure, and symptoms experienced a month after discharge were crucial for the score.
- The PragueMi score demonstrated better accuracy in predicting mortality risks at 6 months and 1 year compared to the existing GRACE score.
Background: Heart failure is a common complication after myocardial infarction (MI) and is associated with increased mortality. Whether remote heart failure symptoms assessment after MI can improve risk stratification is unknown. The authors evaluated the association of the 23-item Kansas City Cardiomyopathy Questionnaire (KCCQ) with all-cause mortality after MI.
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- The study investigates the impact of the rs7767652 minor allele T on mortality risk in patients who have experienced a myocardial infarction (MI) and its association with hypocretin/orexin signaling.
- Data were collected from a registry of patients hospitalized for MI, revealing that those with the TT allele had a higher prevalence of complications like ventricular fibrillation and lower improvements in heart function post-MI.
- Results indicate that reduced hypocretin/orexin signaling linked to the TT variant increases the risk of death after MI, partly due to greater arrhythmic risks and impaired heart recovery.
Background: Left ventricular ejection fraction (EF) is an independent predictor of adverse outcomes after myocardial infarction (MI). However, current data on trajectories and determinants of EF are scarce. The present study aimed to describe the epidemiology of EF after MI.
View Article and Find Full Text PDFBackground: Pheochromocytoma is a neuroendocrine tumour originating from the chromaffin cells of adrenal glands or sympathetic paraganglia. It produces most frequently norepinephrine, epinephrine, and dopamine. As a result of non-specific and variable clinical presentation, pheochromocytoma is difficult to diagnose.
View Article and Find Full Text PDFAims: Recent advances in therapy led to a significant decrease in mortality and morbidity after myocardial infarction (MI). However, little is known about quality of life (QoL) after MI. We examined heart failure (HF)-related quality-of-life (QoL) impairment, its trajectories, and determinants after MI.
View Article and Find Full Text PDFBackground: Inconclusive data exist on risk associated with Lp(a) in patients after myocardial infarction (MI). Aims of the present study were to evaluate the association of Lp(a) level with total mortality and recurrent cardiovascular events.
Design And Methods: Single center prospective registry of consecutive patients hospitalized for acute myocardial infarction between June 2017 and June 2020 at a large tertiary cardiac center with available blood samples drawn <24h of admission.
Aims: The aim of the present paper was to provide an up-to-date view on epidemiology and risk factors of heart failure (HF) development after myocardial infarction.
Methods And Results: Based on literature review, several clinical risk factors and biochemical, genetic, and imaging biomarkers were identified to predict the risk of HF development after myocardial infarction.
Conclusions: Heart failure is still a frequent complication of myocardial infarction.