Publications by authors named "Dominik Janu"
Horm Res Paediatr
October 2021
Article Synopsis
- The study investigates the role of serum acid-labile subunit (ALS) as a potential biomarker for diagnosing growth hormone deficiency (GHD) in children, alongside standard markers IGF-I and IGFBP-3.
- Ninety-one children undergoing GHD diagnosis were analyzed, revealing that IGF-I was the most significant predictor of GHD, with ALS contributing little to the diagnosis.
- The findings conclude that measuring ALS, whether alone or with other biomarkers, does not improve the detection of GHD compared to using IGF-I and IGFBP-3, which performed similarly in diagnostic accuracy.
