Publications by authors named "Dominik Bergmann"
Article Synopsis
- Citrinin (CIT) is a harmful mycotoxin found in grains, fruits, and spices that converts to a significant urinary metabolite called dihydrocitrinone (DHC) after ingestion.
- This study explored how DHC forms complexes with various types of cyclodextrins (CDs), which are sugar-based molecules known to interact with other compounds.
- The research found that modified quaternary-ammonium-γ-cyclodextrin creates the most stable complexes with DHC, while quaternary-ammonium-β-cyclodextrin significantly boosts DHC's fluorescence signal, indicating CD technology could enhance DHC detection methods.
Citrinin (CIT) is a nephrotoxic mycotoxin produced by Penicillium, Monascus, and Aspergillus species. CIT appears as a contaminant in cereals, cereal-based products, fruits, nuts, and spices. During the biotransformation of CIT, its major urinary metabolite dihydrocitrinone (DHC) is formed.
View Article and Find Full Text PDFThe analysis of the nephrotoxic mycotoxin citrinin in food, feed, and physiological samples is still challenging. Nowadays, liquid chromatography coupled with mass spectrometry is the method of choice for achieving low limits of detection. But matrix effects can present impairments for this method.
View Article and Find Full Text PDF(18)O labeling is a well-known method for the stable isotope labeling of proteins and peptides. This study describes a modified procedure for using (18)O labeling on small molecules. Fumonisin B1, a worldwide occurring mycotoxin, which is routinely analyzed by HPLC-MS/MS, was chosen as model compound.
View Article and Find Full Text PDF