Publications by authors named "Dominick J Megna"
Shortage of organ donors is an ongoing limiting factor in lung transplantation (LT). Despite increasing prevalence of asymptomatic COVID-19 infection, positive COVID-19 testing from a potential donor remains a contraindication at many LT centers. In this report, we present the outcomes of LT utilizing an algorithm based on donor clinical presentation, and COVID-19 real-time reverse transcription polymerase chain reaction (RT-PCR) with cycle threshold (Ct) values evaluation.
View Article and Find Full Text PDFArticle Synopsis
- Penetrating aortic ulcers usually happen in arteries that are severely damaged.
- A 46-year-old woman experienced sudden cardiac arrest due to ischemia.
- The cause was a mobile blood clot in her aorta, linked to a penetrating ulcer in the ascending section of the aorta.
Article Synopsis
- - A 65-year-old woman with a right lung transplant developed severe difficulty breathing and was found to have disseminated Mycobacterium tuberculosis (MTB) presenting as an empyema necessitans (EN), leading to hospitalization.
- - During her stay, she experienced daily fevers and was diagnosed with a right-sided chest wall abscess and pleural effusion, where cultures confirmed MTB growth within a week.
- - After starting treatment with multiple antituberculosis medications, she suffered severe side effects, including hemorrhagic pancreatitis and distributive shock, highlighting the challenges of managing MTB infections in organ transplant patients.
Background: Primary graft dysfunction (PGD) is a major cause of early mortality following heart transplant (HT). The International Society for Heart and Lung Transplantation (ISHLT) subdivides PGD into 3 grades of increasing severity. Most studies have assessed risk factors for PGD without distinguishing between PGD severity grade.
View Article and Find Full Text PDFSingle lung transplantation in patients with severe secondary pulmonary hypertension.
J Heart Lung Transplant
September 2019
Background: The optimal transplant strategy for patients with end-stage lung disease complicated by secondary pulmonary hypertension (PH) is controversial. The aim of this study is to define the role of single lung transplantation in this population.
Methods: We performed a retrospective study of lung transplant recipients using the Organ Procurement and Transplantation Network/United Network for Organ Sharing Standard Transplant Analysis and Research registry.