Publications by authors named "Dominic L Maderazo"
J Theor Biol
October 2018
Article Synopsis
- The immune response to infection is initiated by T cells being activated when they encounter dendritic cells that have interacted with pathogens, often occurring in lymph nodes.
- The study uses a hybrid mathematical model to simulate the interactions between T cells and dendritic cells, analyzing how various physiological factors affect the immune response after vaccination.
- Key findings indicate that increasing T cell inflow, limiting their exit, and enhancing dendritic cell numbers are crucial for a faster immune response, while lymph node size and dendritic cell transport methods have a less significant impact.
