[Circulation dynamics of respiratory syncytial virus and its relationship with ambient temperature. 25-year series in Buenos Aires].

Objective: To evaluate changes in RSV seasonality in the last 25 years and their correlation with the mean annual temperature.

Methods: Cross-sectional study, based on RSV and temperature data from the City of Buenos Aires (1995-2019). For each year, we describe the beginning, end, and duration of the RSV season and the correlation with the mean annual temperature.

Pediatric residents' perceptions about the impact of the COVID-19 pandemic on their training.

Introduction. Medical residency programs suffered changes that may have affected academic training during the COVID-19 pandemic. Objectives.

Feeding Management and Albendazole Pharmacokinetics in Pigs.

Albendazole (ABZ) is a methylcarbamate benzimidazole anthelmintic used to control gastrointestinal parasites in several animal species and humans. The type of diet has been identified as a major determinant for ABZ pharmacokinetics in different animal species and humans. The work described here assesses the pattern of the absorption and the systemic availability of ABZ and its metabolites after its oral administration to pigs under different feed management plans.

Unilateral axilo-breast approach (UABA) with gas insufflation versus open conventional hemithyroidectomy: A prospective comparative study.

Background: The objective of this study was to compare with the conventional open approach, the surgical and aesthetic results of endoscopic thyroidectomy via unilateral axillo-breast approach (UABA) with gas insufflation in patients with a unilateral thyroid nodule.

Methods: Between August 2017 and August 2020, a prospective comparative cohort study was carried out in patients proposed for hemithyroidectomy. The patients were assigned to one type of approach (Open or Endoscopic) in a successive manner.

Thyroidectomy via unilateral axillo-breast approach (UABA) with gas insufflation: prospective multicentre European study.

Background: Extracervical approaches for thyroidectomy are seldom explored in the western population. The objective of this study was to evaluate the outcomes of hemithyroidectomy via endoscopic unilateral axillo-breast approach (UABA) with gas insufflation.

Method: Consecutive patients undergoing UABA hemithyroidectomy for symptomatic benign or cytologically indeterminate nodules (Bethesda III lesions) of less than 5 cm from July 2015 to December 2020 at three European institutions were included.

Quantitative exposure assessment and risk characterization for fipronil residues in laying hen eggs.

Poultry production is linked to veterinary drug use to treat diseases. Few ectoparasitic compounds are approved for poultry. Fipronil is a pesticide widely used in agriculture.

Effect of electronic prescriptions on the safety of hospitalized pediatric patients.

Introduction: Prescription errors are the most common cause of preventable errors. Electronic prescription (EP) systems may help to reduce errors and improve the quality of care.

Objectives: To assess the effect of EP on the prevalence of prescription errors and related adverse events (AE) among hospitalized pediatric patients.

[An algorithm for identifying visits due to pediatric lower acute respiratory infections in electronic clinical records].

Background: Due to ambiguities in terminology, acute lower respiratory infections (ALRI) in childhood are frequently not properly recorded, especially during outpatient visits. A tool that accurately identifies them, would assess the impact on respiratory health of massive harms, and design policies to prevent or mitigate their effects. We aimed to design an algorithm that allows identifying children with ALRI based on data from the electronic clinical record (ECR) of the Government of the City of Buenos Aires (GCBA).

Pharmacokinetics and milk excretion pattern of eprinomectin at different dose rates in dairy cattle.

This study aimed at determining the plasma disposition kinetics of eprinomectin (EPM) and EPM excretion pattern through milk after topical administration to dairy cattle at the recommended dose of 0.5 mg/kg and at 1 and 1.5 mg/kg.

Children hospitalized for COVID-19 during the first winter of the pandemic in Buenos Aires, Argentina.

Background: Although there are reports on COVID-19 in pediatrics, the characteristics of the population of each country, its health systems, and how the pandemic was addressed could give the disease distinctive features worldwide. We aimed to describe the characteristics of patients hospitalized for COVID-19 in a tertiary pediatric hospital in the City of Buenos Aires, Argentina.

Methods: We conducted a descriptive study, including all patients hospitalized for COVID-19 from 04/26/2020 to 10/31/2020 in a tertiary pediatric hospital.

Oral and topical extra-label administration of fipronil to laying hens: Assessment of the egg residue patterns.

This experimental work reproduces the fipronil extra-label administration performed by producers in laying hens. The scientific goal was to characterize the residual concentrations in eggs from treated hens and suggest the withdrawal periods that should be respected to avoid risk for consumers. Thirty-four laying hens were allocated into two groups: Group A was treated with fipronil in feed, two single doses of 1 mg kg day ; Group B was administered a single dose of 1 mg kg by the topical route.

Influence of faecal culture media and incubation time on the yield of infective larvae of Haemonchus contortus (Rudolphi 1803).

The aim of this experiment was to determine the yield of Haemonchus contortus third-stage larvae (L3) in faecal cultures in different conditions, including incubation time (7 or 14 days), the addition of inert additives (polystyrene pellets, vermiculite or no additive) and physical condition of the incubated faeces (ground or whole pellets). Twelve groups of 10 cultures each were arranged and incubated at 24 °C to evaluate the interaction of the above-mentioned conditions. Significantly, more L3 (p=0.

[Seroprevalence of anti-Mycoplasma pneumoniae antibodies in otherwise healthy children].

Introduction: Mycoplasma pneumoniae (Mypn) infection could be occurring at an earlier age due to social pheno mena such as attending daycare centers more frequently and earlier than decades ago.

Objective: to estimate the prevalence of anti-Mypn antibodies in children aged 0-12 years, and to explore whether age, attendance to daycare center/school, overcrowding or the presence of children aged below 12 years in the households increase the risk of seropositivity.

Patients And Method: Cross-sectional stu dy including healthy children aged 0-12 years which required blood draws for routine laboratory tests.

[Assessment of the impact of grants awarded by the Sociedad Argentina de Pediatría during the last 20 years (1995-2015)].

Introduction: The Argentine Society of Pediatrics awards grants to young pediatricians, aimed at improving performance and encouraging research.

Purpose: To describe the details of grants awarded; to analyze the proportion of projects that were published and of grantees that remained in areas related to their grant.

Material And Method: Descriptive study, through a self-administered survey.

Instrument to assess research projects that apply for a fellowship by the Argentine Society of Pediatrics: Validation using the Delphi method.

Introduction: The objective of this study was to validate the format and contents of an instrument to assess research projects that apply for a fellowship by the Sociedad Argentina de Pediatría using an expert consultation technique, such as the Delphi method.

Material And Methods: A coordinating group selected a panel of research experts who were members of the Sociedad Argentina de Pediatría,designed, and analyzed each of the rounds of consultations. Semistructured questionnaires were sent by personalized e-mail.

Oxfendazole kinetics in pigs: In vivo assessment of its pattern of accumulation in Ascaris suum.

Ascaris suum is a widespread parasitic nematode that causes infection in pigs with high prevalence rates. Oxfendazole (OFZ) is effective against A. suum when used at a single high oral dose of 30 mg/kg.

Assessment of the long-acting ivermectin formulation in sheep: Further insight into potential pharmacokinetic interactions.

The aim of the current study was to evaluate the in vivo pharmacokinetic of ivermectin (IVM) after the administration of a long-acting (LA) formulation to sheep and its impact on potential drug-drug interactions. The work included the evaluation of the comparative plasma profiles of IVM administered at a single therapeutic dose (200 μg/kg) and as LA formulation at 630 μg/kg. Additionally, IVM was measured in different gastrointestinal tissues at 15 days posttreatment with both IVM formulations.

Measuring adverse events in pediatric inpatients with the Global Trigger Tool.

Introduction: The safety of inpatients is a priority in the health care system. The Global Trigger Tool seems to be suitable to estimate the incidence of adverse events (AE) in pediatric inpatients.

Objetives: To describe the incidence and categories of AE in pediatric inpatients using the Global Trigger Tool and to identify risk factors associated to their development.

Publication of abstracts presented at the National Pediatric Research Meetings of the Argentine Society of Pediatrics: Related factors.

Objective: To estimate the proportion of abstracts presented at National Pediatric Research Meetings that are fully-published and describe their design and factors that influence nonpublication.

Methods: Descriptive and analytical study including all abstracts presented at National Pediatric Research Meetings (1998-2011). One author per study was identified and asked to complete a survey on its design, publication and factors associated with non-publication.

Ivermectin Pharmacokinetics, Metabolism, and Tissue/Egg Residue Profiles in Laying Hens.

The goals were to determine the ivermectin (IVM) plasma pharmacokinetics, tissue and egg residue profiles, and in vitro metabolism in laying hens. Experiments conducted were (1) 8 hens were intravenously treated with IVM and blood samples taken; (2) 88 hens were treated with IVM administered daily in water (5 days) (40 were kept and their daily eggs collected; 48 were sacrificed in groups (n = 8) at different times and tissue samples taken and analyzed); (3) IVM biotransformation was studied in liver microsomes. Pharmacokinetic parameters were AUC = 85.