Publications by authors named "Domingo Alberti"
Management of Metastatic Disease in Campania (MAMETIC): An Observational Multicenter Retrospective and Prospective Trial on Palliative Radiotherapy in an Italian Region. Study Protocol.
Rossella Di Franco Marco Cascella Mario Fusco Valentina Borzillo Esmeralda Scipilliti Domingo Alberti
J Pain Res
April 2022
Article Synopsis
- In the Campania Region of Italy, there were 30,517 new cases of solid cancer in 2019, with approximately 20% of those being metastatic patients, highlighting the need for tailored radiotherapy based on geographic location.
- The MAMETIC Trial is an observational study combining both retrospective and prospective methods to evaluate how palliative radiotherapy impacts cancer-related pain and overall health-related quality of life in metastatic cancer patients, aiming to enroll between 12,500 and 21,000 patients over five years.
- This study serves to identify regional differences in treatment offerings and aims to standardize radiotherapy approaches for metastatic cancer patients within the Campania Region.
Article Synopsis
- The study evaluates the effectiveness of the Clarity-IGRT system in improving prostate positioning and monitoring during radiotherapy for elderly prostate cancer patients.
- It involved 25 patients aged 75-90, using a specific ultrasound technique to align treatment and reduce planning tumor volume margins, which ultimately aims to enhance treatment accuracy and minimize side effects.
- Results showed that patients experienced mild to moderate toxicity, with a manageable level of genitourinary and rectal side effects, suggesting that Clarity-IGRT improves treatment without increasing toxicity.
Introduction: Lung cancer is the leading cause of cancer-related death in Europe and the US. Isolated metastases to skeletal muscle and the mandible are very uncommon.
Case Presentation: This report presents two cases.
Primary non-Hodgkin's lymphoma of the lacrimal sac is an extremely rare presentation of orbital localization of lymphoma. We present a 45-year-old male patient with primary NHL of the lacrimal sac, stage IE, who was treated with surgery and radiotherapy. Fourteen months after the end of radiotherapy the patient is free of disease and does not show any treatment-related toxicity.
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