Publications by authors named "Domenico Rizzato"
Article Synopsis
- Burkitt lymphoma (BL) is a common type of B-cell lymphoma in kids, with many being cured but some showing resistance to treatment.
- Researchers used single-cell transcriptomics to study the differences between patients who respond to therapy and those who don’t, finding that non-responders have more immune cells and a specific gene, Tropomyosin 2 (TPM2), highly expressed in their tumors.
- The study suggests that the level of TPM2 can help predict treatment outcomes for BL patients, highlighting the disease's genetic diversity and potential biomarkers for therapy resistance.
