Biliary complications after liver transplantation--523 consecutive cases in two centers.

Background/aims: Despite various surgical techniques, biliary tract complications (BC) remain a major source of morbidity after liver transplantation (LT).

Methodology: Between April 2000 and November 2008, 523 LTs in 487 recipients (36 re transplantations) were performed as follows: 402 whole deceased donor graft LTs, and 121 partial liver transplantation: 75 living donor liver transplantation, 42 split liver transplantation, and 4 reduced size liver transplantation.

Results: Mean follow-up period was 935 days (range 1-3174), 1, 3 and 5-year survival rates were 78.

Predictors of long-term survival after liver transplantation for hepatocellular carcinoma.

Aims: The aim of this study was to identify predictors of both survival and tumor-free survival of a cohort of 155 patients, with hepatocellular carcinoma (HCC) and cirrhosis, who were treated by orthotopic liver transplantation (OLT).

Methods: From January 1989 to December 2002, 603 OLTs were performed in 549 patients. HCC was diagnosed in 116 patients before OLT and in 39 at histological examination of the explanted livers.

Liver transplantation for Wilson's disease: The burden of neurological and psychiatric disorders.

A retrospective data analysis on liver transplantation for Wilson's disease (WD) was performed among Italian Liver Transplant Centers. Thirty-seven cases were identified. The main indication for liver transplantation was chronic advanced liver disease in 78% of patients.

Surgical treatment of hepatocellular cancer in the era of hepatic transplantation.

Background: This study compares liver resection (LR) or transplantation (LTx) in an attempt to reevaluate the indications for treatment.

Study Design: One hundred fifty-four LRs and 121 LTxs performed from 1985 to 1999 were considered. Survival and recurrence rate, together with age, gender, liver disease, Child-Pugh classification, alpha-fetoprotein (AFP), tumor capsule, vascular invasion, size, number of nodules, histologic grade, and pTNM were considered.

Liver transplantation for hepatocellular cancer: should the current indication criteria be changed?

Liver transplantation (LTx) is the best treatment for hepatocellular carcinoma (HCC), but should be offered only to selected patients. The usual procedure is to transplant only for small and unilobular tumors. The aim of this paper is to verify whether the actual indication criteria are still justified.