Publications by authors named "Domenica Palomaris Mariano Souza"
Biomed Res Int
March 2018
Article Synopsis
- Cake, a by-product of biodiesel, is high in protein and could be used in livestock feed but has antinutritional factors and phorbol esters that limit its use.
- A study on male Wistar rats showed that treatment with hydrolyzed cake (using 5M NaOH) reduced phorbol ester concentration by 98%, indicating effective detoxification.
- Rats fed nonhydrolyzed cake experienced liver degeneration and poor reproductive outcomes, while those given hydrolyzed versions showed no signs of toxicity, demonstrating the safety of the detoxified product.
