Publications by authors named "Domenic R Barbati"

Article Synopsis
  • Hybrid immunity, which occurs after vaccination following infection, offers stronger protection against SARS-CoV-2 by enhancing immune response effectiveness.
  • The study compares immune profiles of individuals with infection only, vaccination only, and hybrid immunity, finding that hybrid immunity results in better antibody performance and activation of immune cells.
  • Results indicate that older adults particularly benefit from hybrid immunity, highlighting the need for vaccination strategies to consider age differences in immune responses.
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Background: The bivalent COVID-19 mRNA boosters became available in fall 2022 and were recommended alongside the seasonal influenza vaccine. However, the immunogenicity of concurrent vs separate administration of these vaccines remains unclear.

Methods: Here, we analyzed antibody responses in health care workers who received the bivalent COVID-19 booster and the influenza vaccine on the same day or on different days through systems serology.

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The bivalent COVID-19 mRNA boosters became available in fall 2022 and were recommended alongside the seasonal influenza vaccine. However, the immunogenicity of concurrent versus separate administration of these vaccines remains unclear. Here, we analyzed antibody responses in healthcare workers who received the bivalent COVID-19 booster and the influenza vaccine on the same day or different days.

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