[Use of porous polytetrafluoroethylene prostheses in reconstructive reoperations in patients with occlusive lesions of the aorta and arteries of the lower limbs].

The use of a new domestic vascular prosthesis "Vitaflon" in reconstructive reoperations on 21 patients was clinically estimated. The positive properties of the prosthesis such as high biological inertia, good plastic properties, strength and reliability allow this prosthesis to be recommended for using in reconstructive reoperations on the vessels.

[State of the progeny of the 1st generation conceived at different times after low-dose irradiation of female rats].

The relation between the antenatal and early postnatal ontogenesis of the progeny and the degree of maturity of oocytes at the time of the whole single gamma-irradiation with doses of 0.25, 0.5 and 1 Gy was studied on 473 first pregnant Wistar rats and 1402 rats of the first generation.

[The antistaphylococcal activity of thionium in in vitro experiments].

The paper deals with the experimental study of antistaphylococcal properties of thionium--a derivative of bis-quarternary ammonium compounds. High bactericide activity of the preparation is revealed as a result; it is preserved under high contents of protein substances in the media. The sensitivity of staphylococcal strains to thionium is not affected by the initial sensitivity of microorganisms to antibiotics.

[Antimicrobial effect of irradiation with ionized plasma].

Ion plasma light flux has been found to possess bacteriostatic effect in vitro and in vivo. Three-fold irradiation with ion plasma of a wound infected by a pathogenic Staphylococcus aureus strain reduced phase I of wound healing by three days and the overall time of healing by four-five days.

[Mutagenic effects of ionized plasma light flux].

The effect of ion plasma light flux on the genomes of auxotrophic Escherichia coli strain and Drosophilla melanogaster has been examined. Essentially no mutagenic effect was found in doses close to therapeutic ones.

[Analysis of plasmid profile of antibiotic-resistant Enterobacteriaceae circulating in hospitals].

Certain pheno- and genotype properties of S. typhimurium and some other representatives of Enterobacteriaceae resistant to antimicrobial drugs were studied. The strains were isolated from children with salmonellosis within 4 months when an infection hospital was subjected to microbiological observation.

[Resistance to antibacterial drugs of Enterobacteriaceae isolated from healthy children and from those with Salmonella infections].

A total of 2329 Enterobacteriaceae strains in bacterial associations isolated from healthy children and children with salmonellosis were tested for their resistance to antimicrobial drugs. It was shown that the aerobic microbial associations isolated from the healthy children contained higher numbers of strains sensitive or resistant to 1-3 antibiotics while the microbial associations from the children patients with salmonellosis treated with antibiotics contained higher numbers of strains resistant to 6-8 antibiotics. Resistance of the aerobic bacterial associations was mainly defined by resistance of E.

[Problems of preventing ischemic heart disease among naval personnel].

The research specific to the incidence of ischemic heart disease (IHD) among ship's crew members, the state of medical care of sailors during the voyage and at seashore and the analysis of the causes of drafting sailors out of the ship because of health problems demonstrated the necessity of improving the existing system of follow-ups for sailors. The obtained results formed the basis for submitting concrete proposals on the organization of dynamic follow-ups during voyages and at shore for sailors with IHD and associated risk factors, the proposals involved detection of early and occult disease forms, risk factors, formation of medical supervision groups, principles of using primary and secondary prevention techniques, continuity of follow-ups at shore and at sea.

[Effect of cyclic 3,5-adenosine monophosphate on the virulence of Salmonella typhimurium].

To study the role of cAMP in the virulence of S. typhimurium, cAMP-producing plasmid pTG 4 was transferred to cAMP-deficient S. typhimurium mutant.

[Characteristics of microbial associations represented by the Enterobacteriaceae family isolated from the feces of healthy children and children with salmonellosis].

Associations formed by microorganisms of the family Enterobacteriaceae in feces have been studied using the principles of ecological investigation. The study has revealed that the associations isolated from children with salmonellosis sharply differ from those isolated from healthy children in the number of species and in the variety of their combinations, as well as in changes in the proportion of different species, observed in multiple investigations.

[Strains of the family Enterobacteriaceae isolated from chronic bacterial carriers of Salmonella typhi and Salmonella schottmuelleri and from healthy persons].

Fecal samples obtained from 51 chronic carriers of S. typhi and S. schottmuelleri and from 35 healthy persons were studied.

[Relation of Salmonella typhi and Salmonella gallinarum auxotrophicity to the ability to grow on Simmons' medium].

A total of 9 S. typhi strains and 1 S. gallinarum strain isolated from clinical material are auxotrophic with respect to tryptophan.

[Transfer of kanamycin resistance among familial strains of Enterobacteriaceae isolated from a chronic bacterial carrier of Salmonella schottmuelleri].

Escherichia coli, Enterobacter aerogenes and S. schottmuelleri were isolated from the large intestine of a bacteriocarrier. E.

[Possibilities of biochemical identification of the Enterobacteriaceae family by conventional methods].

A total of 579 strains of the family Enterobacteriaceae, isolated from differential diagnostic media, were analyzed by means of 20 standard tests. In 1.8% of the analyzed strains their species and genus could not be determined due to unusual reactions in the tests of amino acid decarboxylation and utilization of some carbohydrates.

[Biosynthetic incorporation of fluorescently labelled fatty acids in Escherichia coli].

Escherichia coli cells were cultivated in a medium containing 1-pyrene butanoic acid, a fluorescent probe. Total lipids were extracted from the cells, and the extract was separated by thin-layer chromatography. The fluorescent fractions were examined using spectrofluorimetry.

[Identification of nonspecifically agglutinating strains of enterobacteria].

Eight nonspecific agglutinating enterobacterial strains have been classified with the definite taxon on the basis of the data obtained by the study of their biochemical and serological properties. The possibilities offered by the supplementary methods for the study of such strains in practical laboratories are discussed.

[Limits of the biochemical variability of the Salmonellae isolated from human beings and their possible identification].

The biochemical properties of 217 Salmonella strains isolated from patients, convalescents and carriers have been studied. Salmonellae with changes in a number of characteristics important for microbiological diagnosis have been found. The possibility of their identification is shown.

[Interrelation between the presence in enterobacteria of distinct biological properties and their capacity to colonize the small intestine in the early stage of the development of postradiation dysbacteriosis].

An increase in the percentage of antibiotic resistant and hemolysin-producing enterobacteria occurring in the process of the development of postradiation intestinal dysbacteriosis was due to a sharp increase in the number of such bacteria among the representatives of the genera inhabiting the large intestine of mice (E. coli, E. aerogenes, E.

[Change in the biological properties of salmonellae in acquiring resistance to chloramphenicol].

Mutants of Salmonella typhimurium and Salmonella abony resistant to 40 microgram/ml of chloramphenicol were obtained during selection according to the method of Szybalski on Hottinger broth with increasing concentrations of the antibiotic. By the colony morphology the mutants were divided into 4 groups. The study of the mutant biological properties revealed changes in the growth rate characterized by elongation of the lag-phase and exponential phase, changes in the biochemical activity evident from lower fermentation rate of some carbohydrates and production of hydrogen sulphide and changes in some amino acid dependence.

[Physiological characteristics of Salmonella typhimurium treated with penicillin].

Growing bacteria of the two strains of Salmonella typhimurium differing in the sensitivity levels to UV-light formed multinuclear non-septal filaments in the penicillin-containing nutrient medium. The maximum number of the lifefull filaments was formed by the 4th hour of incubation in the beaf-peptone broth at a temperature of 37 degrees C in the presence of 5 gamma/ml of penicillin. The strains exposed to penicillin were less sensitive to UV-light.

[Study of the sensitivity of a morphological mutant of S. typhimurium to irradiation].

Morphological Salmonella typhimurium LT2 WT--ED 143 mutant was similar by the character of the UV-sensitivity to the lon-mutants of Escherichia coli K-12. The paper treats of the data on the UV-sensitivity of the mutant and the initial strains at various growth phases, by the capacity to restore the irradiated P22 and Felix O bacteriophages and by the effect of various postradiational treatment on the irradiated strains. Data are presented on densitometry of the membrane proteins of the initial and the mutant strains, permitting to associate the unusual morphology, disturbed division and increased UV-sensitivity with the state of the membrane components of the bacterial cell.