Publications by authors named "Doly Pantoja Guerrero"

Background: Acromegaly, although rare, is associated with multiple manifestations and complications; its high morbidity and mortality makes it a challenge. Treatment involves surgery and pharmacological therapies, focusing on biochemical normalization. This study analyzes the biochemical control in Colombian patients with acromegaly, seeking to improve the understanding of the effects of treatments in the management of the disease.

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Aims: Describe the local characteristics, methodology and results of the registry of acromegalic patients in Colombia (RAPACO).

Methods: Multicenter, retrospective study based on the registry of acromegalic patients in Colombia: RAPACO. The data collected included: demographics, diagnosis, approximate time of disease evolution, data on weight, height, body mass index (BMI), neck circumference (NC) abdominal circumference (AC) hip circumference (HC) and waist/hip ratio (WHR); clinical and biochemical data at the time of diagnosis, etiology, immunohistochemistry of the tumor and information related to types of treatment.

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Article Synopsis
  • Acromegaly is a rare disease caused by excess growth hormone, leading to serious long-term complications and a higher mortality risk, making early diagnosis and treatment crucial.
  • A literature review was conducted to emphasize the importance of recognizing associated comorbidities, which significantly impact patient outcomes and quality of life.
  • Effective management requires a comprehensive approach that addresses both the disease and the various comorbid conditions, as many patients are diagnosed late and face multiple health issues.
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