Efficacy of the TuttleNumbNow Intraosseous Method for Pulpal Anesthesia in the Mandibular First Molar: A Prospective, Randomized, Crossover Study.

Introduction: Previous studies on intraosseous (IO) anesthesia as a primary injection have shown high success rates. The TuttleNumbNow (TNN; Orem, UT) is a new primary IO injection technique that has not been scientifically evaluated. Therefore, the purpose of this prospective randomized, crossover study was to evaluate the anesthetic efficacy of the TNN IO technique using the Septoject Evolution needle (Septodont, Saint-Maur-des-Fosses, France) compared with buccal infiltration for pulpal anesthesia in mandibular first molars.

Fat consumption and its association with age-related macular degeneration.

Objective: To evaluate associations between past dietary fat intake and the prevalence of age-related macular degeneration (AMD).

Methods: Six thousand seven hundred thirty-four participants aged 58 to 69 years in 1990-1994 took part in this cohort study. Participants' nutrient intakes were estimated from a food frequency questionnaire at baseline.

MTAS: which way now? Interview by Rebecca Coombes.

asks key players involved in the medical training application service (MTAS) what they would have done differently

Tendon pathology in the foot. The use of corticosteroid injection therapy.

Corticosteroids have been used extensively in the practice of orthopedics and podiatry. It is the authors' opinion that the issue of corticosteroids and their effect on the healing of tendon pathology has not been addressed sufficiently or answered adequately. Few studies have used a well-controlled injury model.

Comparative response of male and female patients with coronary artery disease to exercise rehabilitation.

Male (227) and female (37) participants in a supervised rehabilitation programme for patients with coronary artery disease were compared in relation to their compliance with and response to the programme. The drop-out rate was higher in females (18.9% vs 7.